DFV890
Cat. No.: DC73526
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Chemical Structure
2271394-34-2
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Field of application
DFV890 (IFM-2427) is apotent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation,prevents NLRP3 inflammasome assembly in response to sterile danger signals.
Cas No.: |
2271394-34-2 |
Chemical Name: |
NLRP3 antagonist 2 |
Synonyms: |
NLRP3 antagonist 2;CS-0889900;EX-A8315;SCHEMBL23456785;(R)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-2-(2-hydroxypropan-2-yl)thiazole-5-sulfonimidamide;DFV 890;HY-155876;2271394-34-2 |
SMILES: |
S(C1=CN=C(C(C)(C)O)S1)(=N)(NC(NC1=C2CCCC2=CC2CCCC=21)=O)=O |
Formula: |
C19H24N4O3S2 |
M.Wt: |
420.548861503601 |
Purity: |
>98% |
Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
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