DFV890

  Cat. No.:  DC73526   Featured
Chemical Structure
2271394-34-2
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More than 5000 active chemicals with high quality for research!
Field of application
DFV890 (IFM-2427) is apotent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation,prevents NLRP3 inflammasome assembly in response to sterile danger signals.
Cas No.: 2271394-34-2
Chemical Name: NLRP3 antagonist 2
Synonyms: NLRP3 antagonist 2;CS-0889900;EX-A8315;SCHEMBL23456785;(R)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-2-(2-hydroxypropan-2-yl)thiazole-5-sulfonimidamide;DFV 890;HY-155876;2271394-34-2
SMILES: S(C1=CN=C(C(C)(C)O)S1)(=N)(NC(NC1=C2CCCC2=CC2CCCC=21)=O)=O
Formula: C19H24N4O3S2
M.Wt: 420.548861503601
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
Cat. No. Product name Field of application
DC73526 DFV890 DFV890 (IFM-2427) is apotent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation,prevents NLRP3 inflammasome assembly in response to sterile danger signals.
DC47029 Selnoflast Selnoflast (example 6) is a NLRP3 inhibitor (extracted from patent WO2019008025).
DC44153 MCC7840 MCC7840, a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. MCC7840 can be used for the research of inflammatory diseases.
DC44152 Emlenoflast sodium (MCC7840 sodium) MCC7840 sodium, a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. MCC7840 sodium can be used for the research of inflammatory diseases.
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