JC124

  Cat. No.:  DC45911   Featured
Chemical Structure
1638611-48-9
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More than 5000 active chemicals with high quality for research!
Field of application
JC124 is a specific NLRP3 inflammasome inhibitor. JC124 has anti-inflammatory and neuroprotective effects.
Cas No.: 1638611-48-9
Chemical Name: JC124
Synonyms: JC124;5-Chloro-2-methoxy-N-(4-(N-methylsulfamoyl)phenethyl)benzamide;BDBM50465503;ClC=1C=CC(=C(C(=O)NCCC2=CC=C(C=C2)S(NC)(=O)=O)C=1)OC;HY-120007;GLXC-21011;CS-0068845;5-chloro-2-methoxy-N-{2-[4-(methylsulfamoyl)phenyl]ethyl}benzamide;CHEMBL4277456;SCHEMBL16261128;5-chloro-2-methoxy-N-[2-[4-(methylsulfamoyl)phenyl]ethyl]benzamide;AKOS036901683;G17900;DA-64625;MS-26278;1638611-48-9
SMILES: ClC1C=CC(=C(C=1)C(NCCC1C=CC(=CC=1)S(NC)(=O)=O)=O)OC
Formula: C17H19ClN2O4S
M.Wt: 382.861762285233
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC73526 DFV890 DFV890 (IFM-2427) is apotent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation,prevents NLRP3 inflammasome assembly in response to sterile danger signals.
DC47029 Selnoflast Selnoflast (example 6) is a NLRP3 inhibitor (extracted from patent WO2019008025).
DC45911 JC124 JC124 is a specific NLRP3 inflammasome inhibitor. JC124 has anti-inflammatory and neuroprotective effects.
DC44153 MCC7840 MCC7840, a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. MCC7840 can be used for the research of inflammatory diseases.
DC44152 Emlenoflast sodium (MCC7840 sodium) MCC7840 sodium, a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. MCC7840 sodium can be used for the research of inflammatory diseases.
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