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GSK180

  Cat. No.:  DC70449  
Chemical Structure
1799725-26-0
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More than 5000 active chemicals with high quality for research!
Field of application
GSK180 (GSK-180) is a potent and specific inhibitor of kynurenine-3-monooxygenase (KMO) with IC50 of 6 nM, shows negligible activity against other enzymes on the tryptophan pathway; inhibits the convertion of kynurenine to 3-hydroxykynurenine with IC50 of 2.0 uM in cell-based assays; prevents multiple organ failure in rodent models of acute pancreatitis.
Cas No.: 1799725-26-0
Chemical Name: GSK180
Synonyms: GSK 180;GSK-180
Formula: C10H7Cl2NO4
M.Wt: 276.07
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC70449 GSK180 GSK180 (GSK-180) is a potent and specific inhibitor of kynurenine-3-monooxygenase (KMO) with IC50 of 6 nM, shows negligible activity against other enzymes on the tryptophan pathway; inhibits the convertion of kynurenine to 3-hydroxykynurenine with IC50 of 2.0 uM in cell-based assays; prevents multiple organ failure in rodent models of acute pancreatitis.
DC70127 GSK 065 A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 4.5 nM.
DC70126 GSK 366 A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 2.3 nM and 0.7 nM for human KMO and Pf-KMO, respectively.
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