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GSK 366

Cat. No.: DC70126

Chemical Structure

1953157-39-5

For research use only. We do not sell to patients.

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Field of application

A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 2.3 nM and 0.7 nM for human KMO and Pf-KMO, respectively.

Cas No.:	1953157-39-5
Chemical Name:	GSK 366
Synonyms:	GSK-366;GSK366
Formula:	C₁₇H₁₆ClN₃O₄
M.Wt:	361.782
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC70449	GSK180	GSK180 (GSK-180) is a potent and specific inhibitor of kynurenine-3-monooxygenase (KMO) with IC50 of 6 nM, shows negligible activity against other enzymes on the tryptophan pathway; inhibits the convertion of kynurenine to 3-hydroxykynurenine with IC50 of 2.0 uM in cell-based assays; prevents multiple organ failure in rodent models of acute pancreatitis.
DC70127	GSK 065	A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 4.5 nM.
DC70126	GSK 366	A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 2.3 nM and 0.7 nM for human KMO and Pf-KMO, respectively.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.