GSK2190915 sodium
Cat. No.: DC70142
Chemical Structure
1196070-26-4
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Field of application
A potent, selective FLAP inhibitor with binding IC50 of 2.6 nM; inhibits LTB4 synthesis following ionophore challenge in human whole blood with IC50 of 76 nM (5 h incubation); shows good selectivity over CYP3A4, 2C9, and 2D6; exhibits excellent preclinical toxicology, pharmacokinetics and oral bioactivity.
Cas No.: |
1196070-26-4 |
Chemical Name: |
GSK2190915 sodium |
Synonyms: |
GSK-2190915A;Fiboflapon sodium;AM-803 sodium |
Formula: |
C38H42N3NaO4S |
M.Wt: |
659.8126 |
Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
MSDS
COA
LOT NO. |
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2018-0101 |
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