GSK2190915 sodium

  Cat. No.:  DC70142  
Chemical Structure
1196070-26-4
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More than 5000 active chemicals with high quality for research!
Field of application
A potent, selective FLAP inhibitor with binding IC50 of 2.6 nM; inhibits LTB4 synthesis following ionophore challenge in human whole blood with IC50 of 76 nM (5 h incubation); shows good selectivity over CYP3A4, 2C9, and 2D6; exhibits excellent preclinical toxicology, pharmacokinetics and oral bioactivity.
Cas No.: 1196070-26-4
Chemical Name: GSK2190915 sodium
Synonyms: GSK-2190915A;Fiboflapon sodium;AM-803 sodium
Formula: C38H42N3NaO4S
M.Wt: 659.8126
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC73518 MK-886 MK-886 (L-663,536) is a potent, selective and orally active inhibitor of 5-lipoxygenase-activating protein (FLAP) with IC50 of 30 nM.
DC70142 GSK2190915 sodium A potent, selective FLAP inhibitor with binding IC50 of 2.6 nM; inhibits LTB4 synthesis following ionophore challenge in human whole blood with IC50 of 76 nM (5 h incubation); shows good selectivity over CYP3A4, 2C9, and 2D6; exhibits excellent preclinical toxicology, pharmacokinetics and oral bioactivity.
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