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GSK 494581A

Cat. No.: DC70150

Chemical Structure

909416-67-7

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Field of application

A potent, specific and mixed glycine transporter subtype 1 (GlyT1) inhibitor (pIC50=7.7) and GPR55 agonist (pEC50=6.5); shows no activity across a set of more than 200 validated molecular target assays from diverse classes, including kinases, proteases and other enzymes, GPCRs.

Chemicals Properties Biological activity COA & MSDS Related products Datasheet

Cas No.:	909416-67-7
Chemical Name:	GSK 494581A
Synonyms:	GSK494581A;GSK-494581A
Formula:	C₂₇H₂₈F₂N₂O₄S
M.Wt:	514.588
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC72122	SSR504734	SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC50=18, 15, and 38 nM, respectively). SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activities.
DC70150	GSK 494581A	A potent, specific and mixed glycine transporter subtype 1 (GlyT1) inhibitor (pIC50=7.7) and GPR55 agonist (pEC50=6.5); shows no activity across a set of more than 200 validated molecular target assays from diverse classes, including kinases, proteases and other enzymes, GPCRs.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.