Opiranserin|VVZ-149;VVZ-000149

Cas No.:	1441000-45-8
Chemical Name:	4-butoxy-N-{4-(dimethylamino)oxan-4-ylmethyl}-3,5-dimethoxybenzamide
Synonyms:	Opiranserin;AP031EC2NI;Opiranserin [INN];BDBM50459963;4-Butoxy-N-((4-(dimethylamino)oxan-4-yl)methyl)- 3,5-dimethoxybenzamide;4-Butoxy-N-((4-(dimethylamino)tetrahydro-2H-pyran-4-yl)methyl)-3,5-dimethoxybenzamide;Benzamide, 4-butoxy-N-((4-(dimethylamino)tetrahydro-2H-pyran-4-yl)methyl)-3,5-dimethoxy-;opiranserina;opiransérine;opiranserinum;4-butoxy-N-{4-(dimethylamino)oxan-4-ylmethyl}-3,5-dimethoxybenzamide;EN300-26664290;4-BUTOXY-N-((4-(DIMETHYLAMINO)OXAN-4-YL)METHYL)-3,5-DIMETHOXYBENZAMIDE;4-butoxy-N-{[4-(dimethylamino)oxan-4-yl]methyl}-3,5-dimethoxybenzamide;EX-A7738;VVZ149;CHEMBL4228903;1441000-45-8;DTXSID201337278;opiranserine;VVZ-149;VVZ-149 free base;DA-66357;UNII-AP031EC2NI;OPIRANSERIN [INN];AKOS040742344;Z4395954487;SCHEMBL16233215;OPIRANSERIN [WHO-DD];HY-109067;4-butoxy-N-[[4-(dimethylamino)oxan-4-yl]methyl]-3,5-dimethoxybenzamide;GTPL11298;CS-0033433
SMILES:	O1CCC(CNC(C2C=C(C(=C(C=2)OC)OCCCC)OC)=O)(CC1)N(C)C
Formula:	C₂₁H₃₄N₂O₅
M.Wt:	394.505066394806
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Opiranserin (VVZ-149, VVZ-000149) is a potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM), purine P2X3 receptor antagonist (IC50=0.87 uM) and serotonin 5-HT2A receptor antagonist (IC50=1.3 uM); demonstrates analgesic efficacy for postoperative pain.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC11905	Opiranserin	Opiranserin (VVZ-149, VVZ-000149) is a potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM), purine P2X3 receptor antagonist (IC50=0.87 uM) and serotonin 5-HT2A receptor antagonist (IC50=1.3 uM).