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MAX-40279

  Cat. No.:  DC48860   Featured
Chemical Structure
2070931-57-4
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More than 5000 active chemicals with high quality for research!
Field of application
MAX-40279 is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2070931-57-4
Chemical Name: 7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-1-(4-piperidinyl)-1H-pyrazol-4-ylthieno3,2-dpyrimidin-2-amine
Synonyms: MAX-40279;7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-(1-piperidin-4-ylpyrazol-4-yl)thieno[3,2-d]pyrimidin-2-amine;7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-(1-piperidin-4-ylpyrazol-4-yl)thieno[3,2-d]pyrimidin-2-amine;Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-;Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-;MAX40279;MAX40279;example 31 [CN106366093A];SCHEMBL18410078;example 31 [CN106366093A];DB15191;SCHEMBL18410078;DA-65272;DB15191;AC-36497;DA-65272;HY-145723;AC-36497;DL772G3NN7;HY-145723;DL772G3NN7;7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-(1-(piperidin-4-yl)-1H-pyrazol-4-yl) thieno (3,2-d)pyrimidin-2-amine;7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-(1-(piperidin-4-yl)-1H-pyrazol-4-yl) thieno (3,2-d)pyrimidin-2-amine;CHEMBL4297470;CHEMBL4297470;7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]thieno[3,2-d]pyrimidin-2-amine;CS-0380104;7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]thieno[3,2-d]pyrimidin-2-amine;Thieno(3,2-d)pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-(1-(4-piperidinyl)-1H-pyrazol-4-yl)-;CS-0380104;Thieno(3,2-d)pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-(1-(4-piperidinyl)-1H-pyrazol-4-yl)-;nefextinib [INN];nefextinib [INN];MAX-40279-01;MAX-40279-01;2070931-57-4;2070931-57-4;UNII-DL772G3NN7;UNII-DL772G3NN7;GTPL13213;GTPL13213;EX-A4057;EX-A4057;MS-27862;MS-27862;nefextinib;nefextinib
SMILES: C12C=NC(=NC=1C(=C(S2)C)C1=C(OC)C=C(C=C1)F)NC1=CN(N=C1)C1CCNCC1
Formula: C22H23FN6Os
M.Wt: 438.52
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_32761_DC48860_2070931-57-4
COA
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Cat. No. Product name Field of application
DC49069 MAX-40279 hemiadipate MAX-40279 hemiadipate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemiadipate has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032).
DC48999 MAX-40279 hemifumarate MAX-40279 hemifumarate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemifumarate has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032).
DC48860 MAX-40279 MAX-40279 is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032).
DC44219 FLT3-IN-3 FLT3-IN-3 is a potent FLT3 inhibitor with IC50s of 13 and 8 nM for FLT3 WT and FLT3 D835Y, respectively.
DC28163 5'-Fluoroindirubinoxime 5'-Fluoroindirubinoxime (5’-FIO, compound 13), an Indirubin derivative, is a potent FLT3 inhibitor, with an IC50 of 15 nM.
DC10921 ATH686 ATH686 (ATH-686) is a potent and selective, second-generation inhibitor of mutant FLT3 protein kinase.
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