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MNK/PIM-IN-1

  Cat. No.:  DC47380  
Chemical Structure
2430792-91-7
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More than 5000 active chemicals with high quality for research!
Field of application
MNK/PIM-IN-1 represents an innovative dual MNK/PIM inhibitor with a good pharmacokinetic profile.
Cas No.: 2430792-91-7
Chemical Name: MNK/PIM-IN-1
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_31232_DC47380_2430792-91-7
COA
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Cat. No. Product name Field of application
DC47380 MNK/PIM-IN-1 MNK/PIM-IN-1 represents an innovative dual MNK/PIM inhibitor with a good pharmacokinetic profile.
DC45197 R8-T198wt R8-T198wt is a cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase.
DC44020 PIM1-IN-1 PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity.
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