PIM1-IN-1|CAS 1417630-95-5|DC Chemicals

Cas No.:	1417630-95-5
Chemical Name:	PIM1-IN-1
SMILES:	COCCN1C2=C(C3=NN=C(C4=NC5=C(NCC6CCNCC6)C=CC=C5C=C4)N3N=C2)OCC1
Formula:	C₂₅H₃₀N₈O₂
M.Wt:	474.56
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC47380	MNK/PIM-IN-1	MNK/PIM-IN-1 represents an innovative dual MNK/PIM inhibitor with a good pharmacokinetic profile.
DC45197	R8-T198wt	R8-T198wt is a cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase.
DC44020	PIM1-IN-1	PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity.
DC8604	Pim-1 Inhibitor 2	Potent Pim-1 kinase inhibitor (Ki = 91 nM).
DC9593	Pim1/AKK1-IN-1	PIM/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively; also inhibits MPSK1 and TNIK.