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PI3K-IN-20

  Cat. No.:  DC46266   Featured
Chemical Structure
1845777-61-8
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More than 5000 active chemicals with high quality for research!
Field of application
PI3K-IN-20 is a PI3k inhibitor extracted from WO2017101847 A1, compound 1.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1845777-61-8
Chemical Name: Gilmelisib
Synonyms: Benzenesulfonamide, 2-chloro-N-[5-[3-[2-(dimethylamino)ethoxy]-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl]-2-methoxy-3-pyridinyl]-4-fluoro-;Gilmelisib;2-chloro-N-(5-(3-(2-(dimethylamino)ethoxy)-4-oxopyrido(1,2-a)pyrimidin-7-yl)-2-methoxypyridin-3-yl)-4-fluorobenzenesulfonamide;PI3K-IN-20;Benzenesulfonamide, 2-chloro-N-(5-(3-(2-(dimethylamino)ethoxy)-4-oxo-4H-pyrido(1,2-a)pyrimidin-7-yl)-2-methoxy-3-pyridinyl)-4-fluoro-;EX-A6470;DA-66704;CS-0200428;Gilmelisib [INN];SCHEMBL17379054;compound 25 (WO2015192760A1);2-Chloro-N-(5-(3-(2-(dimethylamino)ethoxy)-4-oxo-4H-pyrido(1,2-a)pyrimidin-7-yl)-2-methoxy-3-pyridinyl)-4-fluorobenzenesulfonamide;2-chloro-N-[5-[3-[2-(dimethylamino)ethoxy]-4-oxopyrido[1,2-a]pyrimidin-7-yl]-2-methoxypyridin-3-yl]-4-fluorobenzenesulfonamide;AKOS040757094;1845777-61-8;MS-30040;GLXC-26940;UNII-B9ZBD8SQ96;G18409;CHEMBL5095067;compound 25 [WO2015192760A1];B9ZBD8SQ96;GTPL11876;HY-139412
SMILES: C1(S(NC2=CC(C3=CN4C(C=C3)=NC=C(OCCN(C)C)C4=O)=CN=C2OC)(=O)=O)=CC=C(F)C=C1Cl
Formula: C24H23ClFN5O5S
M.Wt: 547.99
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC74260 cyclo-CRVLIR cyclo-CRVLIR is a cyclic peptide that binds selectively to p110α RAS binding domain (p110α-RBD) with ITC Kd of 3 uM, blocks p110α/RAS interaction in vitro and KRAS cancer cell lines.
DC72848 Leniolisib phosphate Leniolisib (CDZ173) phosphate is a potent and selective PI3Kδ inhibitor. Leniolisib phosphate has the potential for immunodeficiency disorders treatment.
DC47383 GSK251 GSK251 is a highly potent, highly selective, orally bioavailable inhibitor of PI3Kδ with a novel binding mode.
DC46266 PI3K-IN-20 PI3K-IN-20 is a PI3k inhibitor extracted from WO2017101847 A1, compound 1.
DC42549 Parsaclisib hydrochloride Parsaclisib hydrochloride (INCB050465 hydrochloride) is a potent, selective and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib hydrochloride shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib hydrochloride can be used for the research of relapsed or refractory B-cell malignancies.
DC42415 IHMT-PI3Kδ-372 IHMT-PI3Kδ-372 is a potent and selective PI3Kδ with an IC50 of 14 nM. IHMT-PI3Kδ-372 shows high selectivity over other class I PI3Ks (56∼83 fold) and other protein kinases. IHMT-PI3Kδ-372 can be uesd for chronic obstructive pulmonary disease (COPD) research.
DC42414 Zandelisib Zandelisib is a phosphatidylinositol 3-kinase (PI3K) extracted from patent WO2019183226 A1, Compound Example 1. Zandelisib selectively inhibits p110δ with an IC50 of 3.5 nM. Zandelisib functions as an antineoplastic.
DC40777 MSC2360844(IOA-244 /roginolisib) MSC2360844 is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. MSC2360844 shows highly selective against a panel of 278 additional kinases.
DC28978 Copanlisib dihydrochloride (BAY 80-6946) Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. Copanlisib dihydrochloride has
DC11906 Parsaclisib Parsaclisib (INCB050465) is a potent, selective and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib can be used for the research of relapsed or refractory B-cell malignancies.
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