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piCRAC-1

  Cat. No.:  DC71363  
Chemical Structure
2418049-54-2
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More than 5000 active chemicals with high quality for research!
Field of application
piCRAC-1 is a potent, photoinducible Ca2+ release-activated Ca2+ (CRAC) channel inhibitor. piCRAC-1 alleviates thrombocytopenia and hemorrhage.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2418049-54-2
SMILES: FC(F)(F)C(C=CC=C1F)=C1CN2N=C(C=C2)/N=N/C3=C(C=CC=C3F)F
M.Wt: 384.28
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_35598_DC71363_2418049-54-2
COA
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Cat. No. Product name Field of application
DC71364 5J-4 5J-4 is a potent CRAC inhibitor. 5J-4 decreases the numbers of infiltrated mononuclear cell into the CNS, and significantly decreases the population of infiltrated CD4+ population. 5J-4 reduces the symptoms and delayed the onset of EAE (experimental autoimmune encephalomyelitis) in mouse model of inflammation.
DC71363 piCRAC-1 piCRAC-1 is a potent, photoinducible Ca2+ release-activated Ca2+ (CRAC) channel inhibitor. piCRAC-1 alleviates thrombocytopenia and hemorrhage.
DC70467 GSK-5498A GSK-5498A is a potent, selective small molecule blocker of Calcium-Release Activated Calcium (CRAC) channel with IC50 of 1 uM; completely inhibits calcium influx through CRAC channels, inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells from multiple human and rat preparations.
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