RGX-104|RGX104|cas 610318-03-1

Cas No.:	610318-03-1
Chemical Name:	(R)-2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]-3-methylpropoxy]phenyl]acetic acid hydrochloride
Synonyms:	RGX-104 hydrochloride; RGX-104 HCl; RGX-104; RGX104; RGX 104; SB742881; SB-742881; SB 742881;
SMILES:	C[C@H](CCOC1=CC=CC(=C1)CC(=O)O)N(CC2=C(C(=CC=C2)C(F)(F)F)Cl)CC(C3=CC=CC=C3)C4=CC=CC=C4.Cl
Formula:	C₃₄H₃₄Cl₂F₃NO₃
M.Wt:	632.5452
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

RGX-104 is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene.

In Vivo:

Oral administration of GW3965 or RGX-104 to animals bearing palpable tumors significantly suppresses the growth of multiple cancer types. Strong tumor growth suppression is also observed in animals bearing large tumors. In some instances, the treatment causes partial or complete tumor regression. Responses are seen across a wide spectrum of malignancies, including lung cancer, melanoma, glioblastoma, and ovarian, renal cell, triple-negative breast, and colon cancer[1].

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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