thiotepa

  Cat. No.:  DC9298   Featured
Chemical Structure
52-24-4
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Field of application
N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group.
Cas No.: 52-24-4
SMILES: S=P(N1CC1)(N2CC2)N3CC3
Formula: C6H12N3PS
M.Wt: 189.21
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Thio-TEPA is a DNA alkylating agent, with antitumor activity.
In Vivo: Thio-TEPA (20 mg/kg, i.p.) with total body irradiation (TBI) enhances donor-type blood chimerism during the first 10 weeks but is not dramatically higher than that of TBI group alone. Thio-TEPA alone improves both short- and long-term engraftment in mice[2].
In Vitro: Thio-TEPA exhibits alkylating activity in rat liver slice incubation. Thio-TEPA does not affect the viability of rat liver slices, and is not accumulated in the slices at all doses of 2, 5, 10 mM[1].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC9298 thiotepa N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group.
DC4182 Temozolomide Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer.
DC2099 cis-Diaminedichloroplatinum Cisplatin is an inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity.
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