Vornorexant|CAS 1517965-94-4|DC Chemicals

Cas No.:	1517965-94-4
Chemical Name:	Vornorexant
Synonyms:	TS-142, ORN0829
Formula:	C₂₃H₂₂FN₇O₂
M.Wt:	447.474
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC73482	CVN766	CVN766 (CVN 766) is a potent, exquisitely selective orexin 1 receptor (OX1R) antagonist with IC50 of 8 nM, 1000-fold selective over OX2R.
DC71983	Nivasorexant	Nivasorexant is a potent orexin receptor antagonist.
DC28246	EMPA	EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively.
DC9573	SB-674042	SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.
DC7277	SB-408124	SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively; exhibits 50-fold selectivity over OX2 receptor.
DC8419	SB-334867	SB-334867 is a selective orexin-1 (OX1) receptor antagonist.
DC7495	SB-334867 HCl	SB-334867 is a selective non-peptide orexin OX1 receptor antagonist with a pKb value of 7.2.
DC11439	Nemorexant	ACT-541468 is a dual orexin receptor antagonist.
DC73483	OBPt-9	OBPt-9 is a potent, postivie allosteric potentiator of orexin receptor-mediated signaling, similarly potentiates the response of OXR1 and OXR2 to orexin A.
DC73481	CVN45502	CVN45502 (CVN 45502) is a potent, orally bioavailable, highly selective orexin 1 receptor (Hcrtr1, OX1R) antagonist with binding affinity (pKi) of 7.86 (human Hcrtr1), significantly reduces feeding and body weight in diet-induced obese (DIO).