| DC9314 |
LY 344864 |
LY344864 is a selective receptor agonist with an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.
|
|
| DC11902 |
Minesapride |
Minesapride (DSP-6952) is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c. |
|
| DC11469 |
APD125(Nelotanserin)
Featured
|
Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively. |
|
| DC9059 |
Olanzapine
Featured
|
Olanzapine(LY170053) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist. |
|
| DC9089 |
Ondansetron HCl |
Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy. |
|
| DCAPI1448 |
PALONOSETRON HCL |
A serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is an antiemetic. |
|
| DC9915 |
PF04995274,PF 04995274
Featured
|
PF-04995274 is a 5-HT4 receptor partial agonist. It thought to act centrally as a pro-cognitive agent that being developed for the treatment of Alzheimer's disease (AD). |
|
| DC12183 |
Phenylbiguanide (N-Phenylbiguanide; PBG; 1-Phenylbiguanide) |
Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM. |
|
| DC9318 |
Piboserod
Featured
|
Piboserod (SB 207266) is a selective 5-HT(4) receptor antagonist.
|
|
| DC8795 |
Pimavanserin(ACP-103)
Featured
|
Pimavanserin(ACP-103) is a potent and selective 5-HT2A receptor inverse agonist with mean pIC50 of with 8.7 in the cell-based functional assay. |
|
| DC7492 |
SB 258585 hydrochloride |
Potent and selective 5-HT6 receptor antagonist (pKi = 8.6). |
|
| DC4147 |
Prucalopride
Featured
|
Prucalopride is a selective, high affinity 5-HT receptor agonistfor 5-HT4a and 5-HT4b with Ki of 2.5 nM and 8 nM, respectively. |
|
| DC8289 |
Prucalopride succinate |
Prucalopride succinate is a selective, high affinity 5-HT4 receptor agonist with pKi of 8.6/8.1 for 5-HT4a/4b. |
|
| DC9979 |
PRX-08066
Featured
|
PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that causes selective vasodilation of pulmonary arteries. |
|
| DC9322 |
Ramosetron (Hydrochloride)
Featured
|
Ramosetron Hydrochloride(YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.
|
|
| DC7268 |
Risperidone(R 64 766) |
Risperidone(R 64 766) is a serotonin 5-HT2 receptor blocker(Ki= 0.16 nM) and a potent dopamine D2 receptor antagonist(Ki= 1.4 nM). |
|
| DCAPI1466 |
Rizatriptan Benzoate |
Rizatriptan Benzoate is a selective serotonin 5-HTID receptor agonist which is structurally derived from tryptamine. |
|
| DC8334 |
RS-127445
Featured
|
RS-127445 is a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 1000x selectivity over the closely related 5-HT2A and 5-HT2C receptors. |
|
| DC9313 |
Sarpogrelate (hydrochloride)
Featured
|
Sarpogrelate(MCI-9042) hydrochloride, a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD.
|
|
| DC8878 |
SB 242084 |
SB 242084 is a potent and selective antagonist of 5-HT2C receptor. |
|
| DC4102 |
SB-269970,SB 269970
Featured
|
SB269970 is a potent and selective 5-HT7 receptor antagonist. |
|
| DC9316 |
SB 271046 (Hydrochloride) |
SB271046 Hcl is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9.
|
|
| DC8483 |
SB-399885 HCl
Featured
|
Potent, brain penetrant, orally active 5-HT6 antagonist. Displays > 200-fold selectivity for 5-HT6 over other 5-HT receptors (pKi values are 9.11, 8.81 and 9.02 for human recombinant, native rat and native human 5-HT6 receptors respectively). |
|
| DC8354 |
Intepirdine (SB-742457, RVT-101）
Featured
|
SB-742457(RVT-101) is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects. |
|
| DC9320 |
Setiptiline (maleate) |
Setiptiline is a serotonin receptor antagonist.
|
|
| DC9319 |
Setiptiline |
Setiptiline(Org-8282) is a serotonin receptor antagonist.
|
|
| DC9315 |
Tegaserod (maleate)
Featured
|
Tegaserod maleate is a partial agonist of the 5-HT4 receptor; stimulates the peristaltic reflex and accelerates gastrointestinal transit.
|
|
| DC10309 |
Tianeptine
Featured
|
Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo. |
|
| DC9150 |
Tianeptine sodium salt
Featured
|
Tianeptine sodium salt is a selective facilitator of 5-HT uptake in vitro and in vivo. |
|
| DC11316 |
U-92016A |
U-92016A is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A (Ki = 0.4 nM). |
|
