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ADCs Linker/Click Chemistry

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Cat. No. Product Name Field of Application Chemical Structure
DC44531 (2-Pyridyldithio)-PEG6 acid 2-Pyridyldithio-PEG6 acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC44532 Biotin-sar-oh Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC44533 Biotin-PEG4-PFP ester Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC44707 DBCO-S-S-acid DBCO-S-S-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC44708 Biotin-PEG2-methyl ethanethioate Biotin-PEG2-methyl ethanethioate is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC44709 Azide-C2-Azide Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC44710 Azido-C6-OH Azido-C6-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC44711 Propargyl-Tos Propargyl-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC44712 DBCO-PEG4-GGFG-DX8951 DBCO-PEG4-GGFG-DX8951 is a drug-linker conjugate for ADC with potent antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the non-cleavable ADC linker DBCO-PEG4-GGFG.
DC44786 MC-AAA-NHCH2OCH2COOH MC-AAA-NHCH2OCH2COOH (compound 20) is a cleavable ADC linker that is used for making antibody-drug conjugate (ADC).
DC44787 MP-PEG4-VK(Boc)G-OSu MP-PEG4-VK(Boc)G-OSu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC44788 MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a Camptothecin-linker compound extracted from patent WO2019195665A1, example 4-1. MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a drug-linker conjugate for antibody-drug conjugate (ADC).
DC45373 Bis-sulfone-PEG3-Azide Bis-sulfone-PEG3-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC45920 MCC MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1.
DC45931 6-Oxohexanoic acid 6-Oxohexanoic acid is a non-cleavable modified MMAF-C5-COOH linker and can be used in the synthesis of modified MMAF-C5-COOH, a drug-linker conjugate for ADC.
DC46041 Biotin-PEG4-SS-azide Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC46131 Acid-C3-SSPy Featured Acid-C3-SSPy is a cleavable DBA-DM4 linker used in the synthesis of DBA-DM4, a drug-linker conjugate for ADC.
DC60106 MC-​Ala-​Ala-​Asn(Trt)​-​PAB Featured MC-​Ala-​Ala-​Asn(Trt)​-​PAB, is a hetero bifunctional cross-linker, useful in antibody drug conjugation (ADC). MC-​Ala-​Ala-​Asn(Trt)​-​PAB is a fissionable linker which is specifically activated in a tumor microenvironment. XQN70430 was reported in patent WO 2016026458.
DC46278 DM21 DM21 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC47170 APN-PEG36-tetrazine APN-PEG36-tetrazine is an analogue of APN-PEG4-tetrazine. APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC47918 PPA PPA is an ADC linker (US20060073528A1). PPA can be used for making antibody-drug conjugate.
DC48375 Zuvotolimod Zuvotolimod is a myeloid cell agonist compound-linker for antibody conjugate. Zuvotolimod can be used in the research of cancer and hepatitis.
DC48376 AcBut AcBut is a cleavable Ozogamicin linker used in the synthesis of Ozogamicin, a drug-linker conjugate for ADC.
DC48496 Methyl 1-Boc-azetidine-3-carboxylate Methyl 1-Boc-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Boc-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1
DC48497 N-Boc-cis-4-Hydroxy-D-proline N-Boc-cis-4-Hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-Hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the synth
DC48498 Boc-Hyp-OH Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
DC48499 N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
DC48500 N-Boc-cis-4-hydroxy-L-proline N-Boc-cis-4-hydroxy-L-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
DC48522 1-Cbz-3-Hydroxyazetidine 1-Cbz-3-Hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-3-Hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
DC48536 N-Boc-cis-4-hydroxy-L-proline methyl ester N-Boc-cis-4-hydroxy-L-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

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