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ADCs Linker/Click Chemistry

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Cat. No. Product Name Field of Application Chemical Structure
DC49325 Ethyl azetidine-3-carboxylate hydrochloride Ethyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ethyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
DC49326 D-Proline, 4-hydroxy-, methyl ester hydrochloride D-Proline, 4-hydroxy-, methyl ester hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). D-Proline, 4-hydroxy-, methyl ester hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
DC49327 H-cis-Hyp-OMe hydrochloride H-cis-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-cis-Hyp-OMe hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PR
DC49328 H-Hyp-OMe hydrochloride H-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Hyp-OMe hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]<
DC49329 tans-4-Hydroxy-D-proline methyl ester hydrochloride tans-4-Hydroxy-D-proline methyl ester hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). tans-4-Hydroxy-D-proline methyl ester hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
DC49349 Mal-amido-PEG9-Val-Ala-PAB-SG3200 Mal-amido-PEG9-Val-Ala-PAB-SG3200 is a cleavable ADC linker conjugate used in the synthesis of antibody-drug conjugates (ADCs).
DC49372 1-N-Boc-3-hydroxyazetidine 1-N-Boc-3-hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-N-Boc-3-hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs
DC49385 1-Boc-azetidine-3-carboxylic acid 1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
DC49387 1-Boc-azetidine-3-yl-methanol 1-Boc-azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-yl-methanol is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]
DC49388 H-Glu-OtBu H-Glu-OtBu is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Glu-OtBu is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
DC50025 Deruxtecan Featured Deruxtecan, a topoisomerase I inhibitor, is an exatecan derivative (DX-8951 derivative) with a cleavable pepetide linker and a maleimide group. The maleimide group in Deruxtecan can react with antibody to form antibody-drug conguates (ADC) such as Trastuzumab deruxtecan (DS-8201a), which is a HER2-targeting antibody–drug conjugate.
DC80073 Azido-PEG4-EV-Cit-PAB-MMAE Featured Azido-PEG4-EV-Cit-PAB-MMAE is a precursor of antibody drug conjugate.
DC71929 bisSP1 bisSP1 is an antibody drug conjugates linker.
DC71930 MDTF MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC71931 MDTF free acid MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC71932 NHS-SS-Ph NHS-SS-Ph is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC72509 Sulfo-SPP sodium Sulfo-SPP sodium a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.
DC72510 SC239 SC239 is a cleavable 2-aminophenyl hemiasterlin drug-linker. SC239 can be as the drug-linker for ADC.
DC72511 Mal-VC-PAB-PNP-CDN-A Mal-VC-PAB-PNP-CDN-A is a drug-linker conjugate for ADC.
DC72512 Mal-Val-Ala-PABA-cGAMP Mal-Val-Ala-PABA-cGAMP is a ADC linker that can be connected to a STING agonist. Mal-Val-Ala-PABA-cGAMP can be used for the synthesis of antibody-drug conjugates (ADCs).
DC72513 Fmoc-Ala-Ala-PAB Fmoc-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
DC72514 Mal-VC-PAB-PNP Mal-VC-PAB-PNP is a cleavable ADC Linker (ADC Linker). Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).
DC72515 MC-Ala-Ala-PAB MC-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
DC72516 MP-Ala-Ala-PAB MP-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
DC72757 MC-Gly-Gly-Phe-Boc MC-Gly-Gly-Phe-Boc is involved in the synthesis of Antibody-Drug Conjugates (ADCs) to Trastuzumab. MC-Gly-Gly-Phe-Boc can participate in cancer research.
DC65699 Mal-propyl-Ala-Ala-Asn-PAB Featured Mal-propyl-Ala-Ala-Asn(Trt)-PAB is a hetero bifunctional cross-linker, useful in antibody drug conjugation (ADC).

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