| DC45964 |
Niazinin |
Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity. |
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| DC45967 |
Protoneogracillin |
Protoneogracillin, a furostanol glycoside, shows anti-fungal activity against the plant pathogenic fungus P.oryzae (MMDC=94.0 μM) and cytotoxic activity on K562 cancer cells (IC50=6.6 μM). |
|
| DC45983 |
Tigloylgomisin P |
Tigloylgomisin P, a lignin, has anti-HIV activity with an EC50 of 37 μM. Tigloylgomisin P has anticancer effect. |
|
| DC45989 |
S-6123 |
S-6123 is a potent antimicrobial compound of the oxazolidinone series. S-6123 inhibits ribosomal protein synthesis without inhibiting DNA or RNA synthesis. |
|
| DC45990 |
Clemastanin B |
Clemastanin B, a lignin, has potent anti-influenza activities by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. Clemastanin B targets viral endocytosis, uncoating or ribonucleoprotein (RNP) export from the nucleus. Clemastanin B has antioxidant and anti-inflammatory activities. |
|
| DC45998 |
Cassiaside B |
Cassiaside B, a naphthopyrone, has potent antimicrobial activity. |
|
| DC46010 |
Sanguisorbigenin |
Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA). |
|
| DC46015 |
Pangelin |
Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities. |
|
| DC46021 |
Benurestat |
Benurestat is an orally active urease inhibitor. Benurestat can be used for infected ureolysis research. |
|
| DC46022 |
Ceftaroline fosamil inner salt |
Ceftaroline fosamil (TAK-599) inner salt, a cephalosporin derivative, is an N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil inner salt can be used for the research of MRSA infection. |
|
| DC46030 |
Ceftobiprole medocaril |
Ceftobiprole medocaril is the parenteral prodrug of Ceftobiprole. Ceftobiprole is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA).
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|
| DC46032 |
Antofloxacin hydrochloride |
Antofloxacin hydrochloride is a well tolerate, orally active and broad-spectrum 8-amino-fluoroquinolone with potent antibacterial activities. Antofloxacin hydrochloride shows superior antibacterial activity against gyrA mutation-positive H. pylori strains, especially in Asn87- mutated strains, compared to levofloxacin. Antofloxacin hydrochloride is a weak, reversible inhibitor of CYP1A2 for the treatment of infections caused by a diverse group of bacterial species. |
|
| DC46063 |
Tellimagrandin II |
Tellimagrandin II (Eugeniin), the first intermediate in the 4C1-glucose derived series of ellagitannins, also inhibits antibiotic resistance of drug-resistant Staphylococcus aureus. |
|
| DC46067 |
Chrysophanol tetraglucoside |
Chrysophanol tetraglucoside possesses anti-hypolipidemic and antibacterial activities. |
|
| DC46076 |
Hispidulin 4'-O-β-D-glucopyranoside |
Hispidulin 4'-O-β-D-glucopyranosid, a natural compound, may serve as a potential COVID-19 main protease inhibitor. |
|
| DC46082 |
Kulactone |
Kulactone, a natural bioflavonoid and an inhibitor against jRdRp, possesses antifungal, antibacterial and antiplasmodial activities. Kulactone exhibit no crossing through Blood Brain Barrier (BBB). |
|
| DC46103 |
Valtrate hydrine B4 |
Valtrate hydrine B4 is a natural compound with antifungal activities. |
|
| DC46115 |
Colutehydroquinone |
Colutehydroquinone is an isoflavonoid that can be found in the root bark of Colutea arborescens. Colutehydroquinone exhibits antifungal activity. |
|
| DC46120 |
Homoembelin |
Homoembelin is an antimicrobial compound and has the potential for MDR bacterial infection research. |
|
| DC46133 |
Dehydrobruceine A |
Dehydrobruceine A is a low potent antitrypanosomal agent, with an IC50 of 88.5 nM for Plasmodium falciparum. |
|
| DC46150 |
Yadanziolide B |
Yadanziolide B, a natural indole alkaloid, is a potential H5N1 neuraminidase inhibitor. |
|
| DC46154 |
AZD-7295 |
AZD-7295 is a HCV NS5A protein inhibitor, with an EC50 of 7 nM for GT-1b replicon. |
|
| DC46161 |
Hypoglaunine D |
Hypoglaunine D is an analogue of Triptonine B and acts as an anti-HIV compound. Hypoglaunine D inhibits HIV replication in H9 lymphocytes with an EC50 value of 22 μg/ml. |
|
| DC46165 |
Granilin |
Granilin, a sesquiterpene lactone, can be found in the flower buds of Carpesium triste. Granilin can be used as the bactericide and fungicide. |
|
| DC46180 |
Aureobasidin A(Basifungin)
Featured
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Aureobasidin A (Basifungin), a cyclic depsipetide, is an antifungal antibiotic. Aureobasidin A (Basifungin) A is an inhibitor of the inositolphosphorylceramide synthase AUR1. |
|
| DC46195 |
Epinecidin-1 TFA |
Epinecidin-1 TFA is a multi-functional antimicrobial peptide (AMP) from Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 TFA has antibacterial, antifungal, antiviral, anti-tumor, and immunomodulatory effects. Epinecidin-1 TFA has the potential to be an alternative for current antibiotics. |
|
| DC46268 |
Golotimod TFA |
Golotimod TFA (SCV 07 TFA), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod TFA (SCV 07 TFA) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod TFA (SCV 07 TFA) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2). |
|
| DC46274 |
LolCDE-IN-2 |
LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 inhibits E. coli MG1655 with a MIC of 2 μg/ml. Antibacterial activity. |
|
| DC46279 |
Tizoxanide D4 |
Tizoxanide D4 (TIZ D4) is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities. |
|
| DC46280 |
Tolnaftate (D7) |
Tolnaftate D7 (NP-27 D7) is the deuterium labeled Tolnaftate. Tolnaftate (NP-27) is a synthetic thiocarbamate used as an anti-fungal agent. |
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