| DC45367 |
Latrunculin B |
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity. |
|
| DC45369 |
Octaethylene glycol monododecyl ether |
Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus. |
|
| DC45397 |
4aα,7α,7aα-Nepetalactone |
4aα,7α,7aα-Nepetalactone exhibits antibacterial activity, and inhibits Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi and Enterococcus faecalis. |
|
| DC45405 |
Chamaechromone |
Chamaechromone is a biflavonoid ingredient isolated from the roots of Stellera chamaejasme L. (Thymelaeaceae). Chamaechromone possesses anti-hepatitis B virus (HBV) effects against the surface antigen of HBV (HBsAg) secretion and has insecticidal activities. |
|
| DC45408 |
Nudicaucin B |
Nudicaucin B is a triterpenoid saponi found in Hedyotis nudicaulis. Nudicaucin B has antifungal activities. |
|
| DC45412 |
(-)-Corypalmine |
(-)-Corypalmine (Discretinine), an alkaloid that could be isolated from the stem of Guatteriopsis friesiana, possesses antimicrobial activity. |
|
| DC45422 |
Cheilanthifoline |
Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC50s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively. |
|
| DC45423 |
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone |
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G. lucidum with antimycobacterial activity. |
|
| DC45431 |
3-Oxobetulin |
3-Oxobetulin, an antifungal agent, shows antifungal activities against white rot fungus L. betulina and the brown rot fungus L. sulphureus. |
|
| DC45435 |
3′,4′,5′,5,6,7-Hexamethoxyflavone |
3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL). |
|
| DC45443 |
Epimagnolin A |
Epimagnolin A, a furfuran lignan, shows mild antiplasmodial activities (IC50=5.7 μg/mL) without noticeable toxicity on mammalian normal cells. |
|
| DC45450 |
Haplopine |
Haplopine possesses photo-activated antimicrobial and DNA binding activities. |
|
| DC45458 |
Dehydrotomatine |
Dehydrotomatine is one of major steroidal glycoalkaloids (SGAs) that accumulate in the mature green fruits, leaves and flowers of tomato (Solanum lycopersicum). Dehydrotomatine is against bacteria, fungi, insects and animals. |
|
| DC45459 |
Bismuth subcarbonate |
Bismuth subcarbonate (Bismuth carbonate oxide) is a typical Bi-based semiconductor that is widely applied as antibacterial, sensors, super capacitors, and photocatalysts. Bismuth subcarbonate protects the gastric ulcer from further erosion by gastric acid. |
|
| DC45476 |
1,3-Linolein-2-Olein |
1,3-Linolein-2-Olein, a triglyceride, is an antileishmanial drug. 1,3-Linolein-2-Olein inhibits promatigotes of the parasite (IC50=0.079 ug/ml) and inhibits the growth of amastigotes (IC50= 40.03 ug/ml). |
|
| DC45477 |
(1R)-α-Pinene |
(1R)-α-Pinene is a volatile monoterpene with antimicrobial activities. (1R)-α-Pinene reduces Bacillus cereus population growth, and exhibits repellent effects. |
|
| DC45505 |
Bis(dihydrochelerythrinyl)amine |
Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity. |
|
| DC45515 |
Methyl caffeate |
Methyl caffeate, an antimicrobial agent, shows moderate antimicrobial and prominent antimycobacterial activities. Methyl caffeate also exhibits α-glucosidase inhibition activity, oxidative stress inhibiting activity, anti-platelet activity, antiproliferative activity in cervix adenocarcinoma and anticancer activity in lung and leukmia cell lines. |
|
| DC45517 |
Schisanwilsonin C |
Schisanwilsonin C (Arisanschinin K) shows anti-HBV activity. |
|
| DC45518 |
Tetradehydropodophyllotoxin |
Tetradehydropodophyllotoxin possesses antifungal activity. |
|
| DC45520 |
Wilfortrine |
Wilfortrine is a bioactive sesquiterpene alkaloid. Wilfortrine exhibits immunosuppresive effects. Wilfortrine also can inhibit leukaemia cell growth in mice and shows anti-HIV activity. |
|
| DC45533 |
Prodigiosin hydrochloride |
Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties. |
|
| DC45534 |
(R)-Eucomol |
(R)-Eucomol, a flavonoid derivative, displays marginal antibacterial activity. (R)-Eucomol shows cytotoxic activity against KB and P-388 cells. |
|
| DC45535 |
Ascr#18 |
Ascr#18, an ascaroside, is a hormone of nematodes. Ascr#18 is expressed during nematode development. Ascr#18 increases resistance in Arabidopsis, tomato, potato and barley to viral, bacterial, oomycete, fungal and nematode infections. |
|
| DC45536 |
Fumitremorgin B |
Fumitremorgin B is a tremorgenic mycotoxin. Fumitremorgin B exhibits significant antifungal activities, with MICs of 6.25-50 μg/mL. |
|
| DC45537 |
FR179642
Featured
|
FR179642 is a key intermediate in the synthesis of the echinocandin antifungal Micafungin. FR179642 is the cyclic peptide nucleus of the echinocandin-like antifungal lipopeptide FR901379. |
|
| DC45538 |
Betulin diacetate |
Betulin diacetate, a natural diterpene, is an anti-AID agent and also possesses anti-cancer activity. |
|
| DC45539 |
Clazuril |
Clazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle. |
|
| DC45540 |
Cinchonine monohydrochloride hydrate |
Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis. |
|
| DC45541 |
GRL-0496 |
GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM. |
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