DC28651 |
m-PEG4-Ms |
m-PEG4-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28652 |
Azido-PEG6-NHS ester |
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC28653 |
Azido-PEG9-acid |
Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28655 |
N-Boc-PEG2-bromide |
N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28656 |
N-Boc-PEG7-alcohol |
N-Boc-PEG7-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28663 |
m-PEG7-Ms |
m-PEG7-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28665 |
Hydroxy-PEG3-SS-PEG3-alcohol |
Hydroxy-PEG3-SS-PEG3-alcohol is also a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28666 |
m-PEG9-Amine |
m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28667 |
Azido-PEG5-acid |
Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as the conjugate CPT-APO (CPT: Camptothecin).
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DC28668 |
Propargyl-PEG4-Br |
Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28685 |
Thalidomide-NH-PEG7 |
Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader. |
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DC28698 |
DBCO-Sulfo-Link-biotin |
DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28699 |
Gemcitabine-O-Si(di-iso)-O-Mc |
Gemcitabine-O-Si(di-iso)-O-Mc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28719 |
Fmoc-NH-PEG5-CH2COOH |
Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28720 |
Fmoc-NH-PEG8-CH2COOH |
Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28766 |
DC10SMe |
DC10SMe is a DNA alkylator, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC10SMe exhibits IC50s of 15 pM, 12 pM, and 12 pM for Ramos, Namalwa, and HL60/s cancer cells, respectively. |
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DC28767 |
DC4SMe |
DC4SMe, a phosphate prodrug of cytotoxic DNA alkylator DC4, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer. |
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DC28768 |
DC44SMe |
DC44SMe, a phosphate prodrug of cytotoxic DNA alkylator DC44, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44SMe exhibits IC50s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer. |
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DC28769 |
DC4 |
DC4, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4 can be used for the targeted treatment of cancer. |
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DC28770 |
DC44 |
DC44, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44 can be used for the targeted treatment of cancer. |
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DC28861 |
Fmoc-Asp-NH2 |
Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC28907 |
MMAE-SMCC |
MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate. |
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DC29011 |
NH-bis(C1-Boc) |
NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC). |
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DC29012 |
Mal-amido-(CH2COOH)2 |
Mal-amido-(CH2COOH)2, compound 7a, is a maleimidoethyl-containing intermediate for hydrophilic ADC linker. |
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DC29013 |
Tetraethylene glycol monotosylate
Featured
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Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC29014 |
Mal-L-PA-NH-Boc |
Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC29015 |
BMPS |
BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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DC29017 |
Hydroxy-PEG3-(CH2)2-Boc |
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196). |
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DC29018 |
N3-PEG3-CH2CH2-Boc |
N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC29020 |
Azido-PEG4-CH2-Boc |
Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
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