Cat. No. | Product name | CAS No. |
DC23780 |
MKT-077
Featured
MKT-077 (FJ-776) is a highly water-soluble (>200 mg/ml) rhodacyanine dye that exhibits significant antitumor activity, binds to Hsp70 family member, mortalin (mot-2), and abrogates its interactions with p53. |
147366-41-4 |
DC21317 |
ML 086 (CID-1674999)
Featured
ML 086 is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM). |
1177148-36-5 |
DC7998 |
ML 204
Featured
ML 204 isa blocker of TRPC4 channels (IC50 values are 0.96 and 2.6 μM in fluorescent and electrophysiological assays, respectively). |
5465-86-1 |
DC9874 |
ML-348(ML348)
Featured
ML 348(ML348) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). |
899713-86-1 |
DC21325 |
ML 792
Featured
ML 792 is a potent, seletive SUMO-activating enzyme (SAE) inhibitor with IC50 of 3 nM and 11 nM for SAE/SUMO1 and SAE/SUMO2, respectively. |
1644342-14-2 |
DC23103 |
Adenosine, [P(R)]-5'-O-[(R)-hydroxymercaptophosphinyl]-P-thioadenylyl-(2'→5')-, cyclic nucleotide, ammonium salt (1:2)
Featured
ML RR-S2 CDA ammonium salt is a synthetic cyclic dinucleotide derivative that functions as a highly potent agonist of STING, enhances binding affinity to STING and activates all known human STING alleles. |
1638750-96-5 |
DC10908 |
ML RR-S2 CDA
Featured
ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING). |
1638241-89-0 |
DC23691 |
ML090
Featured
ML090 (ML-090, CCG-44699, Fluoflavin, NSC 179821) is a potent, selecitve inhibitor of NADPH oxidase 1 (NOX1) with IC50 of 90 nM, displays no significant activities against NOX2, 3 and 4 (IC50>10 uM).. |
531-46-4 |
DC11463 |
Cruzain-IN-1(ML092)
Featured
ML092 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM. |
1199523-24-4 |
DC7467 |
ML-098
Featured
ML-098 is an activator of the GTP-binding protein Rab7 (EC50 = 77.6 nM) that demonstrates selectivity against the related GTPases cdc42, Ras, Rab-2A, and Rac1 (EC50s = 588.8, 346.7, 158.5, and 794.3 nM, respectively). |
878978-76-8 |
DC12333 |
ML-109
Featured
ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM. |
1186649-91-1 |
DC10142 |
ML130
Featured
ML-130 is a potent and selective inhibitor of NOD1; displays 36-fold selectivity for NOD1 over NOD2 (IC50 values are 0.56 and >20 μM for NOD1 and NOD2 respectively). |
799264-47-4 |
DC7901 |
ML-141
Featured
ML141 is a potent, selective and reversible non-competitive inhibitor of Rho family GTPase cdc42 with IC50 of 200 nM. |
71203-35-5 |
DC10466 |
ML-18
Featured
ML18 is Bombesin receptor subtype 3 (BRS-3) antagonist (IC50 = 4.8 μM). ML-18 inhibits lung cancer growth. |
1422269-30-4 |
DC22156 |
ML-191
Featured
ML-191 is a potent, selective GPR55 antagonist with 160 nM potency for GPR55 and >100-fold selectivity against GPR35, CB1 and CB2. |
931695-79-3 |
DC8850 |
ML-213(CID-3111211)
Featured
ML-213 (CID-3111211) is a selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener (EC50 values are 230 and 510 nM for KV7.2 and KV7.4 respectively). |
489402-47-3 |
DC7771 |
ML216
Featured
ML216(CID-49852229) is a potent inhibitor of the DNA unwinding activity of BLM helicase; showing similar IC50s of 3.0 and 0.97 μM for full length BLM and BLM636–1298 respectively. |
1430213-30-1 |
DC10793 |
ML221
Featured
ML221 is an antagonist of the apelin (APJ) receptor. |
877636-42-5 |
DC7781 |
ML-224
Featured
ML-224 (ANTAG3) is a selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice. |
1338824-21-7 |
DC10790 |
ML-239
Featured
ML-239 is an inhibitor of cancer stem cells, displaying greater than 23-fold selective inhibition of a breast cancer stem cell-like cell line (EC50 = 1.18 µM) over an isogenic control cell line (EC50 = 27.6 µM). |
1378872-36-6 |
DC8576 |
ML-240
Featured
ML-240 is am ATP-competitive inhibitor of p97 ATPase (IC50 = 110 nM). |
1346527-98-7 |
DC9307 |
ML-241
Featured
ML241 is a potent, selective, and reversible inhibitor of the AAA ATPase p97 (IC50=100 nM). It blocks p97-dependent proteasome substrate with an IC50 of 3500 nM. |
1346528-06-0 |