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Cat. No. Product Name Field of Application Chemical Structure
DC11420 AS-1517499 Featured AS1517499 is a potent STAT6 inhibitor with IC50 of 21 nM.
DC10086 AS1842856 Featured AS1842856 is a potent and cell-permeable Foxo1 inhibitor with an IC50 of 30 nM.
DC3112 AS-252424 Featured AS-252424 is a novel, potent and selective inhibitor of PI3Kγ with IC50 of 33 nM.
DC20035 AS2717638 Featured AS2717638 is an oral active lysophosphatidic acid receptor 5 (LPA5) antagonist in rodents. AS2717638 also significantly improves PGE2-, PGF2α-, and AMPA-induced allodynia.
DC11460 AS604850 Featured AS-604850 is a selective, ATP-competitive PI3Kγ inhibitor with IC50 of 250 nM, over 80-fold selectivity for PI3Kγ than PI3Kδ/β, and 18-fold more selective for PI3Kγ than PI3Kα.
DC11407 Asapiprant(BGE-175) Featured Asapiprant (BGE-175) is a potent and specific antagonist of human PGD2/PTGDR signaling with Ki of 0.44 nM. BGE-175 is currently in a Phase 2 clinical trial to test whether it can prevent disease progression and mortality in older patients hospitalized wit
DC20622 Asciminib Featured Asciminib (ABL-001) is a potent and selective allosteric ABL1 inhibitor with IC50 of 0.25 nM in BCR–ABL1-transformed BaF3 cells.
DC1049 Ascomycin (Immunomycin,FK-520) Featured Ascomycin is an analog of tacrolimus with immunosuppressive, neurotrophic and antifungal activities.
DC10704 Asimadoline (EMD-61753) Featured Asimadoline (EMD-61753) is a drug which acts as a peripherally selective κ-opioid receptor (KOR) agonist.
DC10781 ASK1-IN-1 Featured ASK1-IN-1 is an apoptosis signal regulating kinase 1 (ASK1) inhibitor extracted from patent WO2016025474A1, Compound 4.
DC21100 Gusacitinib (ASN-002) Featured ASN-002 (Gusacitinib, ASN002) is a novel and potent dual inhibitor of SYK/JAK kinases with IC50 of 5-46 nM in biochemical assays.
DC10558 ASP 7663 Featured ASP 7663 is a selective TRPA1 activator (EC50 values are ~0.5 μM in human, mouse and rat).
DC7359 Asp-3026 Featured ASP3026 is a novel and selective inhibitor for ALK with IC50 of 3.5 nM.
DC20218 ASP5878 Featured ASP5878 is a selective FGFR inhibitor, to treat FGFR3-dependent urothelial cancer with or without chemoresistance.
DC11174 ASP7657 Featured ASP7657 (ASP-7657) is a potent, selective, orally active prostaglandin EP4 receptor antagonist with Ki values of 6.02 nM and 2.21 nM for rat and human EP4 receptors, resepctively.
DC10588 ASP-9521 Featured ASP-9521 is a potent, selective and orally available AKR1C3 inhibitor with an IC50 of 11 nM for human AKR1C3.
DC11163 AST-3424 Featured AST-3424 (OBI-3424, TH-3424) is a first-in-class, novel prodrug that selectively targets cancers overexpressing the enzyme AKR1C3, OBI-3424 is a highly selective prodrug that is converted by AKR1C3 to a DNA alkylating agent.
DC8641 Astragaloside A Featured Astragaloside A, also known as astragaloside IV, is known to have diverse protective effects for the cardiovascular, immune, digestive, and nervous systems.
DC11447 Astragaloside IV Featured Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
DC20695 ASTX660(Tolinapant) Featured ASTX660 is a novel potent IAP antagonist that targets the BIR3 domain of cIAP1/2 and XIAP with IC50 of 12 nM and <40 nM.
DC7361 Asunaprevir Featured Asunaprevir (BMS-650032) is a potent hepatitis C virus (HCV) NS3 protease inhibitor.
DC20080 AT-1002 Featured AT-1002, a 6-mer synthetic peptide, is a tight junction regulator and absorption enhancer.
DC26065 AT-127 Featured AT-127 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 1.18 nM.
DC20699 AT-130 Featured AT-130 is a potent inhibitor of HBV capsid assembly, inhibits wild-type HBV replication with IC50 of 2.4 uM.
DC7362 AT13148 Featured AT13148 is a novel, oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity; AKT, p70S6K, PKA, ROCK, and SGK inhibitor.
DC8167 Onalespib(AT13387,ATI13387X) Featured AT13387 is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells, displays a long duration of anti-tumor activity.
DC7363 AT-406 Featured AT-406 (formerly known as SM-406) is an orally bioavailable potent IAP (inhibitor of apoptosis protein) of XIAP, cIAP1, and cIAP2 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, respectively.
DC7364 AT-56 Featured AT-56 is a selective, competitive, and highly bioavailable inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) with a Ki value of 75 µM.
DC9676 AT7519 Featured AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM; less potent to CDK3 and little active to CDK7.
DC1025 AT7519 HCL Featured AT7519 is a novel multi-CDK inhibitor for CDK1/cyclin B, CDK2/Cyclin A, CDK3/Cyclin E, CDK4/Cyclin D1, CDK5/p35 and CDK6/Cyclin D3 with IC50 of 210 nM, 47 nM, 360 nM, 100 nM, 13 nM and 170 nM, respectively.

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