Cat. No. | Product name | CAS No. |
DC46153 |
(±)-ErSO
Featured
(±)-ErSO is the racemate of ErSO. ErSO is a selective anticipatory unfolded protein response (a-UPR) activator. |
2407860-40-4 |
DC46158 |
CAY10698
Featured
CAY10698 (compound 1) is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 5.1 μM. CAY10698 is inactive against 5-LOX, 15-LOX-1, 15-LOX-2 and COX-1/2. |
684236-01-9 |
DC46162 |
Vazegepant hydrochloride
Featured
Vazegepant (BHV-3500) hydrochloride is a highly soluble CGRP receptor antagonist. Vazegepant hydrochloride is the first intranasal gepant for migraine. Vazegepant hydrochloride may be helpful in effective management of COVID-19 associated pulmonary inflammation. |
1414976-20-7 |
DC46172 |
IL-17 modulator 3
Featured
IL-17 modulator 3 is an IL-17 modulator (US20200247785A1). IL-17 modulator 3 can be used for the research of inflammation, cancer and autoimmune diseases. |
2467731-88-8 |
DC46180 |
Aureobasidin A(Basifungin)
Featured
Aureobasidin A (Basifungin), a cyclic depsipetide, is an antifungal antibiotic. Aureobasidin A (Basifungin) A is an inhibitor of the inositolphosphorylceramide synthase AUR1. |
127785-64-2 |
DC46181 |
ECBN hydrochloride
Featured
A-30912A nucleus hydrochloride is the product of the reaction catalyzed by Echinocandin B (ECB) deacylase. |
1029890-89-8 |
DC46182 |
Didemnin B
Featured
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer. |
77327-05-0 |
DC46183 |
TPX-0022(CSF1R-IN-2)
Featured
TPX-0022 (CSF1R-IN-2) is a potent inhibitor of MET/CSF1R/SRC with enzymatic kinase inhibition IC50s of 0.14 nM, 0.71 nM and 0.12 nM, respectively. TPX-0022 modulates the tumor immune microenvironment in preclinical models. |
2271119-26-5 |
DC46184 |
YUM70
Featured
YUM70 is a potent inhibitor of glucose-regulated protein 78 (GRP78) inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. |
423145-35-1 |
DC46189 |
Teduglutide
Featured
Teduglutide (ALX-0600, Gattex, Revestive, TAK 633) is an analogue of human glucagon-like peptide-2 (GLP-2) and binds to the GLP-2 receptors. Teduglutide prolongs the intestinotrophic properties of GLP-2 in animal models. |
197922-42-2 |
DC46190 |
PRI-724
Featured
PRI-724 (C-82 prodrug, ICG-001 analog) is a potent and specific inhibitor that disrupts the interaction of β-catenin and CBP. |
1422253-38-0 |
DC46193 |
BRM/BRG1 ATP Inhibitor-1
Featured
BRM/BRG1 ATP Inhibitor-1 is an orally active inhibitors of Brahma Homolog (BRM)/SMARCA2 with IC50 below 0.005 µM. |
2270879-17-7 |
DC57020 |
Avatrombopag
Featured
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 may be useful in the treatment of patients with thrombocytopenia. |
570406-98-3 |
DC60055 |
NB-598
Featured
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. NB-598 suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells. NB-598 reduced basolaterally secreted radioactivity in cholesterol, cholesterol ester, PL and TG. Furthermore, NB-598 suppressed the basolateral secretion of apolipoprotein (apo) B. When microsomes prepared from control Caco-2 cells were incubated with 10 microM NB-598, acyl CoA:cholesterol acyltransferase (ACAT) activity was inhibited slightly. |
131060-14-5 |
DC60057 |
DUN73423
Featured
DUN73423 is a RET/KDR-Selective Inhibitor of RETV804M Kinase with IC50 = 7 nM. DUN73423 was listed in ACS Med Chem Lett . 2020 Feb 28;11(4):497-505 (compound 5). DUN73423 has CAS#2414373-42-3, no formal name For the convenience of scientific communication, we named it as DUN73423 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature . |
2414373-42-3 |
DC60058 |
Gly-AMC HCl
Featured
Gly-AMC, also known as L-Gly-7-Amino-4-Methylcoumarin, is a probe and chromphore substrate for aminopeptidase. it is useful to make the C-terminal conjugate of ubiquitin with 7-amino-4-methylcoumarin (Ub-AMC), which is an important probe for fluorescence-based anal. of deubiquitinating enzyme (DUB) activity. |
208459-17-0 |
DC60059 |
Capmatinib hydrochloride
Featured
Capmatinib, also known as INCB28060 and INC280, is an orally bioavailable inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. c-Met inhibitor INC280 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein. Capmatinib was approved in 2020. |
1865733-40-9 |
DC60060 |
PTN57491
Featured
PTN57491 is an key intermediate chemical to synthesize antiviral drugs remdesivir and GS441524. PTN57491 has CAS#1355357-49-1, has no formal name For the convenience of scientific communication, we named it as PTN57491 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature . |
1355357-49-1 |
DC60061 |
Mefentrifluconazole
Featured
Mefentrifluconazole is a fungicide on cereals. |
1417782-03-6 |
DC60062 |
5-Hydroxymethyl-2'-deoxyuridine
Featured
5-Hydroxymethyldeoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM). |
5116-24-5 |
DC60063 |
LUN42518
Featured
LUN42518, also known as Phentolamine Analogue 1, is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist. LUN42518 has CAS#47142-51-8, no formal name For the convenience of scientific communication, we named it as LUN42518 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature. |
47142-51-8 |
DC60064 |
MW-2474
Featured
MW-2474 is an inhibitor of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agent. |
2414591-05-0 |