Cat. No. | Product name | CAS No. |
DC60207 | N-(1,2-Dimethylbenzimidazol-5-yl)-1-[(3-fluorophenyl)methyl]pyrrolo[3,2-c]pyridine-2-carboxamide Featured | 920978-76-3 |
DC71294 |
BPKDi
Featured
BPKDi is a potent bipyridyl PKD inhibitor with IC50s of 1 nM, 9 nM and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes. |
1201673-28-0 |
DC71300 |
Branaplam hydrochloride
Featured
Branaplam (LMI070; NVS-SM1) hydrochloride is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model. |
1562338-39-9 |
DC71308 |
GB1211
Featured
GB1211 is an orally available galectin-3 (Gal-3) inhibitor. |
1978336-95-6 |
DC71316 |
MC2652
Featured
MC2652 (compound 1a) is a potent LSD1 inhibitor. MC2652 displays high inhibiting effects in MV4-11 and NB4 leukaemia cells. MC2652 shows antiproliferative activity against prostate cancer LNCaP cells. |
2771425-46-6 |
DC71321 |
ET-JQ1-OH
Featured
ET-JQ1-OH is an allele-specific BET inhibitor. |
2421153-77-5 |
DC71335 |
Norastemizole
Featured
Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities. |
75970-99-9 |
DC71352 |
Picotamide
Featured
Picotamide is a combined inhibitor of thromboxane A2 (TxA2) synthase and receptor. Picotamide has antiplatelet activity. Picotamide promotes the reduction of microalbuminuria and the inhibition of growth of carotid plaques in diabetes. Picotamide can be used for researching acute or chronic cardiovascular diseases. |
32828-81-2 |
DC71359 |
UR-MB108
Featured
UR-MB108 (Compound 57) is a potent, selective ABCG2 (BCRP) inhibitor with an IC50 of 79 nM. UR-MB108 is stable in blood plasma. |
2412461-98-2 |
DC71376 |
ABBV-318
Featured
ABBV-318 is a potent Nav1.7/ Nav1.8 blocker, with IC50s of 2.8 μM and 3.8 μM for hNav1.7 and hNav1.8, respectively. ABBV-318 can be used for the research of pain. |
1802848-94-7 |
DC71386 |
(2E)-OBAA
Featured
(2E)-OBAA is a potent phospholipase A2 (PLA2) inhibitor, with an IC50 of 70 nM. (2E)-OBAA induces apoptosis of HUVEC cells. (2E)-OBAA blocks Melittin-induced Ca2+ influx in Trypanosoma brucei, with an IC50 of 0.4 μM. |
221632-26-4 |
DC71390 |
Ribavirin carboxylic acid
Featured
Ribavirin carboxylic acid (TR-COOH) is a metabolite of ribavirin, ribavirin has strong antiviral activity. |
39925-19-4 |
DC71417 |
YSK 05
Featured
YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo. |
1318793-78-0 |
DC71418 |
BPC157
Featured
BPC157 (Bepecin, PL 14736), a small, chemically synthesised pentadecapeptide and a partial sequence of the human gastric juice protein BPC, which has been shown to be safe in clinical trials for inflammatory bowel disease and may be able to cure intestinal anastomosis dehiscence. |
137525-51-0 |
DC71430 |
NHS-NH-(diethylamino)ethyl benzoate
Featured
NHS-NH-(diethylamino)ethyl benzoate is a compound that can be used for N-glycan labeling. |
2050902-45-7 |
DC71440 |
FAP-2286
Featured
FAP-2286, a fibroblast activation protein (FAP)-binding peptidic macrocycle coupled to the radionuclide chelator DOTA. FAP-2286 has potent affinity to human FAP protein with a Kd of 1.1 nM. FAP-2286, a tumor imaging agent, is a useful tool for the research of positron emission tomography (PET). FAP-2286 has antitumor activity. |
2581741-18-4 |
DC71463 |
WX-081
Featured
WX-081, an anti-tuberculosis agent, displays excellent anti-mycobacterial activity against M. tuberculosis H37Rv and low cytotoxicity. |
1859978-72-5 |
DC71466 |
EDA-DA
Featured
EDA-DA is an unnatural dipeptide building block (an ethynyl-D-alanine and a D-alanine). It incorporates a biorthogonal alkyne group into peptidoglycan (PG) through MurF in the cytoplasmic pathway, which enables selective labeling via a click-chemistry reaction. EDA-DA allows labeling of PG in Gram-positive (B. subtilis), Gram-negative (E. coli and C. trachomatis), Mycobacterium (M. smegmatis) and moss plastids (P. patens) with azide modified fluorescent dyes such as Alexa Fluor 488. |
87156-01-2 |
DC71474 |
VP-4604
Featured
VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) agent. VP-4604 exhibits significant microbial growth inhibition toward Staphylococcus aureus (ATCC 43300) with MIC of 4-8 µg/mL. VP-4604 inhibits the growth of methicillin‐resistant Staphylococcus aureus with growth inhibition >95%. |
64268-93-5 |
DC71510 |
Ansofaxine hydrochloride
Featured
Ansofaxine hydrochloride (LY03005, LPM570065), a triple reuptake inhibitor, inhibits serotonin, dopamine and norepinephrine reuptake with IC50 values of 723, 491 and 763 nM, respectively. |
916918-84-8 |
DC71536 |
FABPs ligand 6
Featured
FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with KD values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research. |
2988135-14-2 |
DC71542 |
2-MPPA
Featured
2-MPPA (GPI-5693) is an orally active and selective glutamate carboxypeptidase II (GCP II; PSMA) inhibitor with an IC50 of 90 nM. |
254737-29-6 |