| A148 |
KRN330 Biosimilar(Anti-GPA33 Reference Antibody)
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| A149 |
Minomic patent anti-Glypican 1 Biosimilar(Anti-GPC1 / Glypican-1 Reference Antibody)
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| A150 |
Nih Patent Anti-Glypican-2 Biosimilar(Anti-GPC2 / Glypican 2 Reference Antibody)
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| A151 |
Codrituzumab Biosimilar(Anti-GPC3 / Glypican-3 Reference Antibody)
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Codrituzumab (GC33) is a humanized monoclonal antibody targeting human GPC3 (glypican-3), with high affinity (Kd of 0.673 nM). GPC3 is an oncofetal protein expressed on the cell surface of hepatocellular carcinoma (HCC). Codrituzumab induces antibody-dependent cellular cytotoxicity (ADCC) and inhibits tumor growth. |
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| A153 |
Glembatumumab Biosimilar(Anti-GPNMB Reference Antibody)
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Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-agent coupling (ADC) with antitumor activity. |
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| A154 |
DS-6157 Biosimilar(Anti-GPR20 Reference Antibody)
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| A155 |
KHK patent anti-CRTH2 Biosimilar(Anti-GPR44 / PTGDR2 / CD294 Reference Antibody)
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| A156 |
BNC101 Biosimilar(Anti-GPR49 / LGR5 Reference Antibody)
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| A157 |
Multiple seq-one in animal Biosimilar(Anti-GPR73 / PROKR1 Reference Antibody)
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| A158 |
Talquetamab Biosimilar(Anti-GPRC5D Reference Antibody)
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Talquetamab (JNJ-64407564) is a humanized bispecific antibody that binds to GPRC5D (member of G protein-coupled receptor family C5 group D) and CD3 to induce T cell-mediated killing of GPRC5D-expressing MM cells through T cell recruitment and activation. Talquetamab (JNJ-64407564) has antitumor activity. |
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| A159 |
Regeneron patent anti-GREM1 Biosimilar(Anti-GREM1 / Gremlin Reference Antibody)
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| A160 |
UCB patent anti-Gremlin-1 Biosimilar（Anti-GREM1 / Gremlin Reference Antibody）
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| A161 |
Indusatumab Biosimilar(Anti-GUCY2C Reference Antibody)
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Indusatumab (5F9 Monoclonal antibody) is an anti-human GUCY2C (Guanylate cyclase 2C) monoclonal antibody. |
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| A162 |
KHK patent anti-Haptoglobin Biosimilar(Anti-Haptoglobin Reference Antibody)
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| A163 |
U3-1565 Biosimilar(Anti-HBEGF Reference Antibody)
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| A164 |
KHK2866 Biosimilar(Anti-HBEGF Reference Antibody)
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| A165 |
Tuvirumab Biosimilar（Anti-HBsAg Reference Antibody）
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Tuvirumab (OST 577; SDZ-OST 577) is a human IgG1 subclass monoclonal antibody directed against HBV surface antigen (HBsAg). Tuvirumab binds specifically and with high affinity (K=3.6 nM) to HBsAg. Tuvirumab has the potential for chronic hepatitis B research.
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| A166 |
LY2787106 Biosimilar(Anti-Hepcidin / HAMP Reference Antibody)
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| A167 |
Ludwig-Maximilians U. anti_Hepsin Biosimilar(Anti-Hepcidin / HAMP Reference Antibody)
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| A168 |
TAK-701 Biosimilar(Anti-HGF / SF Reference Antibody)
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| A169 |
Rilotumumab Biosimilar(Anti-HGF / SF Reference Antibody)
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Rilotumumab (AMG 102) is an anti-HGF (anti-hepatocyte growth factor) monoclonal antibody, inhibits HGF/MET-driven signaling. Rilotumumab shows anti-tumor activity, and can be used in castration-resistant prostate cancer (CRPC) and solid tumor research. |
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| A170 |
Ficlatuzumab Biosimilar（Anti-HGF / SF Reference Antibody）
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Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion. |
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| A171 |
Genentech patent anti-HGFA Biosimilar（Anti-HGFA Reference Antibody）
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| A172 |
Amivantamab Biosimilar（Anti-HGFR / c-Met Reference Antibody）
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Amivantamab (JNJ-61186372) is a human EGFR-MET bispecific antibody with immune anticancer activity. Amivantamab inhibits ligand binding, promotes endocytosis and degradation of receptor-antibody complexes, and induces Fc-dependent cytokinesis in macrophages and antibody-dependent cytotoxicity in natural killer cells. |
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| A173 |
Onartuzumab Biosimilar（Anti-HGFR / c-Met Reference Antibody）
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Onartuzumab (MetMAb) is a unique, humanized and affinity-matured monovalent (one-armed) monoclonal antibody against the MET receptor. Onartuzumab potently inhibits HGF binding and receptor phosphorylation and signaling. Onartuzumab has antibody-like pharmacokinetics and antitumor activity. |
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| A174 |
Emibetuzumab Biosimilar（Anti-HGFR / c-Met Reference Antibody）
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Emibetuzumab (LY2875358) is a humanized bivalent MET antibody (IgG4 type). Emibetuzumab shows high neutralization and internalization activities, resulting in inhibition of both HGF-dependent and HGF-independent MET pathway activation and tumor growth. Emibetuzumab can be used in study of cancer. |
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| A175 |
Telisotuzumab Biosimilar（Anti-HGFR / c-Met Reference Antibody）
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Telisotuzumab (ABT-700) is a human recombinant bivalent antibody, a therapeutic antibody against the hepatocyte growth factor receptor (MET) that binds c-Met with high affinity and inhibits c-Met signaling. Telisotuzumab has antitumor activity. |
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| A176 |
SAIT301 Biosimilar（Anti-HGFR / c-Met Reference Antibody）
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| A177 |
Korea RIBB patent anti-cMet Biosimilar（Anti-HGFR / c-Met Reference Antibody）
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| A178 |
Metheresis patent anti-Met Biosimilar（Anti-HGFR / c-Met Reference Antibody）
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