Cat. No. | Product name | CAS No. |
DC60279 |
ART812
Featured
ART812 is a DNA polymerase Polθ inhibitor with an IC50 value of 7.6 nM. ART812 has an IC50 value of 240 nM for cell based microhomology-mediated end joining (MMEJ)[1][2]. |
2607138-82-7 |
DC60280 |
CCG 203769
Featured
CCG-203769 is a selective G protein signaling (RGS4) inhibitor, which blocks the RGS4-Gαo protein-protein interaction in vitro with an IC50 of 17 nM. |
410074-60-1 |
DC60281 |
Bucolome
Featured
Bucolome is a CYP2C9 inhibitor, used as an uricosuric agent or anti-inflammatory agent. |
841-73-6 |
DC60282 |
Potassium Channel Activator 1
Featured
Carbamic acid, N-[2,4-dimethyl-6-(4-morpholinyl)-3-pyridinyl]-, phenylmethyl ester is a new invention for treating, one or more disorders or conditions wherein the dopaminergic system is disrupted, such as one or more disorders or conditions independently selected from the group consisting of: schizophrenia and other psychotic states; mood disorders ADHD; aggression; movement disorders. |
908608-06-0 |
DC60283 | CDDO-TFEA Featured | 932730-52-4 |
DC60284 |
GN13
Featured
GN13 is a cell-permeable, nucleotide-active-state-selective inhibitor of Gαs, with high selectivity over other G protein subfamilies. GN13 binds to Gαs/GNP with KD of 0.19 μM. |
|
DC60285 |
GD20
Featured
GD20 is a cell-permeable, nucleotide-inactive-state-selective inhibitor of Gαs, with high selectivity over other G protein subfamilies. GD20 inhibits Gαs steady-state GTPase activity with IC50 of 1.15 μM. |
|
DC60286 |
(R)-69
Featured
(R)-69 is a 5-HT2AR partial agonists with EC50 of 41 nM, and shows 4.6-fold/29-fold selectivity over 5HT2BR/5HT2CR. (R)-69 has substantial brain permeability in mouse pharmacokinetic studies and dose not possess locomotor-stimulating or reinforcing activity. |
|
DC60288 |
(R)-70
Featured
(R)-70 is a 5-HT2AR partial agonists with EC50 of 110 nM, and shows 6.4-fold/51-fold selectivity over 5HT2BR/5HT2CR. (R)-70 has substantial brain permeability in mouse pharmacokinetic studies and dose not possess locomotor-stimulating or reinforcing activity. |
|
DC60289 |
Antitubercular agent-30
Featured
Antitubercular agent-30 is an antibacterial agent against Mycobacterium tuberculosis (MIC=50 μg/mL). Antitubercular agent-30 has little cytotoxic effect on murine macrophage cells (LD85=~100 μg/mL). |
384857-54-9 |
DC60291 | WAY-620645 Featured | 742116-45-6 |
DC60292 | WAY-115880 Featured | 142995-02-6 |
DC60294 |
SphK1&2-IN-1
Featured
SphK1&2-IN-1 is a SphK inhibitor targeting to SphK1 and SphK2. SphK1&2-IN-1 has thermal stability. |
1415662-57-5 |
DC60290 |
c-Met-IN-15
Featured
c-Met-IN-15 (compound S3) is a c-Met kinase inhibitor. c-Met-IN-15 inhibits c-Met kinase activity of 21.1% at the concentration of 10 μM. |
330572-32-2 |
DC60295 | PAZ-417 Featured | 481629-87-2 |
DC60296 | WAY-620057 Featured | 32585-54-9 |
DC60297 | CL-302396 Featured | 38942-57-3 |
DC60298 | WAY-349858 Featured | 771503-50-5 |
DC60301 | WAY659100 Featured | 308830-70-8 |
DC60302 |
WAY641966
Featured
WAY-641966 is a anti-prion agent. |
259870-32-1 |
DC60303 |
WAY320461
Featured
WAY-320461 is a FAK inhibitor. |
491839-65-7 |
DC60305 | WAY328178 Featured | 909090-75-1 |