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Pitavastatin Calcium

  Cat. No.:  DCAPI1470   Featured
Chemical Structure
147526-32-7
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More than 5000 active chemicals with high quality for research!
Field of application
Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH o
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 147526-32-7
SMILES: C(C[C@@H](C[C@@H](/C=C/C1C(C2CC2)=NC2=CC=CC=C2C=1C1C=CC(F)=CC=1)O)O)(=O)[O-].C(C[C@@H](C[C@@H](/C=C/C1C(C2CC2)=NC2=CC=CC=C2C=1C1C=CC(F)=CC=1)O)O)(=O)[O-].[Ca+2]
Formula: (C25H23FNO4)2.Ca
M.Wt: 880.98
Purity: >99%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Pitavastatin Calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells.
References: [1]. Mukhtar RY, et al. Pitavastatin. Int J Clin Pract. 2005 Feb;59(2):239-52. [2]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor. Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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