16:0 TAP is a cationic derivative of trimethylammonium linked with two 16-carbon fatty acid tails. 16:0 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. Reagent grade, for research use only.

18:0 TAP is a cationic derivative of trimethylammonium linked with two 18-carbon fatty acid tails. 18:0 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. Reagent grade, for research use only.

18:1 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. Reagent grade, for research use only.

DC-6-14 is a cationic lipid that can be used for drug delivery, gene transfection and vaccine delivery. DC-6-14 may be used for research into in vitro and in vivo nucleic acid and protein delivery. Reagent grade, for research use only.

12:0 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 12-carbon fatty acid tails. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

14:0 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 14-carbon fatty acid tails. The lipid has low toxicity and is biodegradable.

16:0 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 16-carbon fatty acid tails. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

18:0 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 18-carbon fatty acid tails. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

14:1 EPC (Tf Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 14-carbon fatty acid tails with single alkene groups in each tail. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

18:1 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 18-carbon fatty acid tails with single alkene groups in each tail. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

16:0-18:1 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with one 16-carbon fatty acid tail and one 18-carbon fatty acid tail with a single alkene group. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

16:0 DAP, 1,2-dipalmitoyl-3-dimethylammonium-propane, is a cationic lipid that can be used to formulate lipid nanoparticles (LNPs). 18:0 DAP also serves as a pH-sensitive transfection reagent. Reagent grade, for research use only.

DORI, N-(2-hydroxyethyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium bromide, is an ionizable cationic lipid with lower cytotoxicity and high transfection efficiency. Reagent grade, for research use only.

DOBAQ, N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium, is a cationic lipids with a quaternary amine and unsaturated hydrocarbon chains. DOBAQ also serves as a pH-sensitive transfection reagent. Reagent grade, for research use only.

Belumosudil, also known as KD-025 and WHO11343, is an orally bioavailable inhibitor of ROCK-II that is greater than 200-fold selective over ROCK-I (IC50s = 105 nM and 24 µM, respectively). Belumosudil (SLx-2119; 40 µM) induces significant down-regulations of Tsp-1 and CTGF mRNA levels in PASMC.

Eperisone hydrochloride is a compound used in the treatment of musculoskeletal disorders as a muscle relaxant via blocking of calcium channels.

Tizanidine is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system.

Arcturus lipid 2 analog (Lipid 2,2 (9,9) 4C CH3) is an analog of Arcturus lipid 2((Lipid 2,2 (8,8) 4C CH3)) with chain adjusted to C9 instead of C8.

Rebecsinib (17S-FD-895) is a selective inhibitor of splicing-mediated adenosine deaminase acting on RNA1 (ADAR1) activation. Rebecsinib prevents ADAR1p150-splice isoform expression and malignant A-to-I editing-mediated LSC self-renewal at doses that spare normal HSPCs and are well tolerated in rat, rabbit, and non-human primate (NHP) pre-IND toxicokinetic (TK), pharmacokinetic (PK), and pharmacodynamic (PD) studies.

1,2-Dioleoyl-3(R)-trimethylammoniumpropane (R-DOTAP) is a cationic lipid and the more immunologically active isomer of DOTAP.Lipoplexes containing R-DOTAP and encapsulating siRNA targeting the gene encoding aromatase, CYP19A1, decrease aromatase activity in MCF-7 breast cancer cells.1 Vaccination with a peptide epitope from human papillomavirus (HPV) 16 protein E7 in R-DOTAP-containing liposomes induces IFN-γ production by CD8+ T cells and tumor-infiltrating lymphocytes (TILs) and decreases tumor size in a murine cervical cancer model.2 Subcutaneous immunization with recombinant influenza B hemagglutinin using R-DOTAP as an adjuvant increases IL-2 and IFN-γ production in CD4+ T cells isolated from mouse draining lymph nodes and spleen.