Cat. No. | Product name | CAS No. |
DC60395 |
Meclozine
Featured
Meclozine is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness. |
569-65-3 |
DC60396 | (S)-SHA 68 Featured | 847555-75-3 |
DC60397 | 1-Methyl-3-amino-4-cyanopyrazole Featured | 21230-50-2 |
DC60398 |
TFMT
Featured
TFMT (Trifluoromethyl-tubercidin) inhibits methyltransferase 1 (MTr1) through interaction at its S-adenosyl-l-methionine binding pocket to restrict influenza virus replication. TFMT is active against influenza A virus (IAV) and influenza B virus (IBV) but not hazara virus (HAZV) or Issyk-Kul virus (ISKV). |
1854086-05-7 |
DC60399 |
DT2216-isomer
Featured
DT2216-isomer is an isomer of DT2216. Compared to DT-2216, DT2216-isomer has a S-chiral carbon which links to the nitrogen atom of the aniline group. DT2216 is a potent and selective Bcl-xL-specific degrader. DT2216 is highly active against Bcl-xL-dependent T cell lymphomas. DT2216 selectively killed various Bcl-xL-dependent TCL cells including MyLa cells in vitro. In vivo, DT2216 alone was highly effective against MyLa TCL xenografts in mice without causing significant thrombocytopenia or other toxicity. Furthermore, DT2216 combined with ABT199 (a selective Bcl-2 inhibitor) synergistically reduced disease burden and improved survival in a TCL PDX mouse model dependent on both Bcl-2 and Bcl-xL. |
|
DC60400 |
Gramicidin S
Featured
Gramicidin S is an anttiboitics. Gramicidin S reduces the cell number of planktonic cells within 20-40 min at a concentration of 40-80 μg/mL. Gramicidin S kills the cells of pre-grown biofilms at concentrations of 100-200 μg/mL, such that no re-growth is possible. The translocation of the peptide into the cell interior and its complexation with intracellular nucleotides, including the alarmon ppGpp, can explain its anti-biofilm effect. The successful treatment of persistently infected root canals of two volunteers confirms the high effectiveness of GS. The broad Gramicidin S activity towards resistant, biofilm-forming E. faecalis suggests its applications for approval in root canal medication. |
113-73-5 |
DC60401 |
DL-AP-3
Featured
DL-AP-3, or AP-3 is a Potent metabotropic glutamate receptor antagonist. |
20263-06-3 |
DC60402 |
Dov-Val-Dil-OH
Featured
Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the polymerisation of tubulin. |
133120-90-8 |
DC60403 |
Bacteriopheophytin
Featured
Bacteriopheophytin, also known as Bacteriopheophytin a, is a Pigment which is the degradation product of bacteriochlorophyll. |
17453-58-6 |
DC83220 |
ALC-0315 analgous-1
Featured
ALC-0315 analgous-1 is an ethanolamine ionizable lipid with both ester bonds located adjacent to C8 relative to the amine head. The introduction of ester linkages can improve the clearance of the lipid in the liver. This compound is analgous to ALC-0315. |
2430034-17-4 |
DC60405 |
C13-112-tri-tail
Featured
C13-112-tri-tail is an ionizable lipid molecule containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries. |
1381861-96-6 |
DC60406 |
C13-113-tri-tail
Featured
C13-113-tri tail is an ionizable lipid molecule containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries. |
1381861-86-4 |
DC60407 |
C13-112-tetra-tail
Featured
C13-112-tetra-tail is an ionizable lipid molecule containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. |
1381861-92-2 |
DC60408 |
C13-113-tetra-tail
Featured
C13-113-tetra tail is an ionizable lipid molecule containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. |
1381861-97-7 |
DC60409 |
14:0 TAP
Featured
TAP (14:0) A cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery. TAP has been proven to be efficient for in vitro and in vivo transfection applications, which makes it one of the most widely used cationic lipids for gene transfection applications. Reagent grade, for research use only. |
197974-74-6 |
DC60411 |
Boc-Val-Cit-PAB-PNP
Featured
Boc-Val-Cit-PAB-PNP is useful and cleavable linker for ADC (antibody drug conjugate) synthesis. |
870487-10-8 |
DC60412 |
VUN74640
Featured
VUN74640, also known as CCR6 antagonist 1, is a CCR6 antagonist. VUN74640 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs). This product has no formal name at the moment. |
588674-64-0 |
DC60413 |
MC-VC-Pab-mmaf
Featured
MC-VC-PAB-MMAF, also known as MC-Val-Cit-PAB-MMAF and Vc-MMAF, is a MMAF (Monomethylauristatin F) derivative with a reactive linker have a maleimido functional group in the end. MC-VC-PAB-MMAF is a useful compound to make MMAF antibody drug conjugates for cancer treatment. MMAF is a potent tubulin polymerization inhibitor with antitumor activity. |
863971-17-9 |
DC60414 |
WAY-111543
Featured
WAY-111543 is a bioactive chemical. |
868269-74-3 |
DC60415 |
MitoBlock-6
Featured
MitoBlock-6 is an Augmenter of liver regeneration (ALR) inhibitor. MitoBloCK-6 attenuated the import of Erv1 substrates into yeast mitochondria and inhibited oxidation of Tim13 and Cmc1 in in vitro reconstitution assays. |
303215-67-0 |
DC60416 |
SUN59716
Featured
SUN59716 is a key intermediate for chemical synthesis of cenobamate. This product has no formal name at the moment. |
1259059-71-6 |
DC60417 |
EN106
Featured
EN106 is a potent inhibitor of FEMIB. EN106 targets FEM1B, an E3 ligase recently discovered as the critical component of the cellular response to reductive stress. By targeting C186 in FEM1B, EN106 disrupts recognition of the key reductive stress substrate of FEM1B, FNIP1. |
757192-67-9 |