| DC12333 |
ML-109
Featured
|
ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM. |
|
| DC7781 |
ML-224
Featured
|
ML-224 (ANTAG3) is a selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice. |
|
| DC10221 |
MLR-1023 |
MLR-1023 is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals. |
|
| DC11165 |
MLS6585 |
MLS6585 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies.. |
|
| DC3160 |
Montelukast Sodium
Featured
|
Montelukast belongs to a group of medications known as leukotriene receptor antagonists. |
|
| DC10326 |
Mozavaptan |
Mozavaptan (OPC31260) is a orally effective, nonpeptide vasopressin V2 receptor antagonist with an IC50 of 14 nM. |
|
| DC10437 |
MRE-269
Featured
|
MRE-269 is an active metabolite of selexipag, and acts as a selective IP receptor agonist. |
|
| DC12258 |
MRS1186 |
MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM. |
|
| DC7203 |
MRS 2578
Featured
|
MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors. |
|
| DC8822 |
MSX-122
Featured
|
MSX-122 is a n orally bioavailable inhibitor of CXCR4 with potential antineoplastic and antiviral activities. |
|
| DC11270 |
MSX-130
Featured
|
MSX-130 is CXCR4 Antagonist. |
|
| DC9507 |
MTEP (hydrochloride) |
MTEP Hcl is a potent, selective and non-competitive mGlu5 antagonist with IC50 and Ki of 5 nM and 16 nM, respectively. |
|
| DCAPI1550 |
Naftopidil |
Naftopidil is an α-1-Adrenergic receptor antagonist and an antihypertensive. |
|
| DC10455 |
NE-100
Featured
|
NE100 hydrochloride is a potent and selective σ1 receptor antagonist (Ki = 0.86 nM) that displays > 55-fold selectivity over σ2 receptors and > 6000-fold selectivity over D1, |
|
| DCAPI1592 |
Nebivolol hydrochloride |
Nebivolol hydrochloride is a highly selective β1-adrenoceptor antagonist |
|
| DC7472 |
Nedocromil |
Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma. |
|
| DC11469 |
APD125(Nelotanserin)
Featured
|
Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively. |
|
| DC11550 |
Netazepide |
Netazepide (YF476, Sograzepide) is a potent, selective and orally active gastrin/CCK-2 antagonist with IC50 of 0.1 nM. |
|
| DC11171 |
NFEPP |
NFEPP is a novel potent, selective pH-dependent μ-opioid receptor (MOR) agonist with a low pKa, shows significantly lower affinity compared with fentanyl at pH 7.4. |
|
| DC8836 |
NIBR189
Featured
|
NIBR 189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively). |
|
| DC10114 |
Nifenalol
Featured
|
Nifenalol is a beta-adrenoceptor antagonist. |
|
| DC9520 |
NKP608 |
NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo. |
|
| DC12351 |
NMI 8739 |
NMI 8739 is a dopamine D2 autoreceptor agonist, which is an amine conjugate of the DHA carrier and the neurotransmitter dopamine. |
|
| DC11386 |
NNZ-2591
Featured
|
NNZ2591 (cyclo-L-glycyl-L-2-allylproline)1 is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life, stability, and oral bioavailability. |
|
| DC12198 |
N-Oleoyl glycine |
N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. |
|
| DC8583 |
Asenapine Maleate
Featured
|
Novel psychopharmacologic agent. Displays antagonist activity at 5-HT, dopamine, noradrenalin and histamine receptor subtypes (pKi values are 8.60, 8.40, 10.15, 9.75, 10.46, 8.84, 9.60, 9.94, 8.85, 8.90, 8.84, 9.38, 8.95, 8.93, 8.9, 9.49, 8.91, 9.00 and 8 |
|
| DC4136 |
NPS-2143 HCL |
NPS 2143 hydrochloride is a selective CaSR (Ca2+-sensing receptor) inhibitor and antagonist, shown to block increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells with an IC50 of 43 nM. NPS 2143 hydrochlori |
|
| DC7214 |
NPS-2143(SB 262470A ) |
NPS-2143(SB 262470A ) is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively. |
|
| DC11269 |
MSX-127（NSC23026）
Featured
|
NSC-23026, also known as MSX-127, is a CXCR4 receptor modulator. |
|
| DC7701 |
NVP-QAV680 |
NVP-QAV680 is a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases. |
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