| DC12298 |
Octreotide acetate (SMS 201-995 (acetate))
Featured
|
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently. |
|
| DC9059 |
Olanzapine
Featured
|
Olanzapine(LY170053) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist. |
|
| DC10370 |
Olcegepant hydrochloride |
Olcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP. |
|
| DC9396 |
Olcegepant
Featured
|
Olcegepant(BIBN 4096; BIBN 4096BS) is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor(IC50= 0.03 nM).
|
|
| DCAPI1464 |
Olmesartan |
Olmesartan Acid is an angiotensin II receptor antagonist that prevents the binding of angiotensin II, thus preventing vasoconstriction. |
|
| DC9179 |
Olmesartan MedoxoMil |
Olmesartan medoxomil(Olmetec; Benicar; CS 866) is an angiotensin II receptor antagonist which is used as an anti-hypertensive. |
|
| DC10384 |
Olodaterol
Featured
|
Olodaterol (BI1744) is a long acting β2-adrenoceptor agonist with an EC50 of 1.4±0.08 nM. |
|
| DC9248 |
Olodaterol(BI-1744) hydrochloride
Featured
|
Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs. |
|
| DC11043 |
Omidenepag
Featured
|
Omidenepag is a potent, selective agonist human EP2 receptor with binding IC50/EC50 of 10/1.7 nM, >500-fold selectivity over EP1, EP3 and EP4 receptors; Omidenepag is the active form of Omidenepag Isopropyl (OMDI). |
|
| DC11044 |
Omidenepag Isopropyl
Featured
|
Omidenepag Isopropyl (DE-117, OMDI) is the prodrug of Omidenepag, which is a potent, selective agonist human EP2 receptor; demonstrates excellent IOP-lowering activities following ocular administration in ocular normotensive monkeys, Omidenepag Isopropyl (OMDI) is a clinical candidate for the treatment of glaucoma. |
|
| DC9089 |
Ondansetron HCl |
Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy. |
|
| DC10630 |
ONO-7300243
Featured
|
ONO-7300243 is a novel, potent LPA1(Lysophosphatidic Acid Receptor) antagonist with an IC50 of 160 nM. |
|
| DC9610 |
ONO-AE3-208 |
ONO-AE3-208(AE 3-208) is an EP4 antagonist; suppresses cell invasion, migration, and metastasis of prostate cancer.
|
|
| DC7425 |
HQL-79 |
Orally active and specific inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS) (IC50 = 6 μM). Antiallergic and anti-inflammatory. |
|
| DC7218 |
Org 27569 |
Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity. |
|
| DC7109 |
Otenabant (CP-945598 free base)
Featured
|
Otenabant (CP945598) is a recently discovered selective, high affinity, competitive CB1 receptor antagonist with Ki of 0.7 nM. |
|
| DC8281 |
Ozanimod (RPC1063)
Featured
|
Ozanimod (RPC1063) is a selective S1P1R modulator |
|
| DC9134 |
Paliperidone |
Paliperidone (9-hydroxyrisperidone) is a dopamine antagonist of the atypical antipsychotic class of medications. |
|
| DCAPI1448 |
PALONOSETRON HCL |
A serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is an antiemetic. |
|
| DC7970 |
ACT058362 (Palosuran)
Featured
|
Palosuran (ACT-058362) is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2 nM. |
|
| DC9675 |
Pardoprunox.HCl(SLV-308)
Featured
|
Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist. |
|
| DC6911 |
pardoprunox (SLV308)
Featured
|
Pardoprunox(SLV-308) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist; D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist (IA = 50% and 67%, respectively) and 5-HT1A receptor (pKi = 8.5) full agonist (IA |
|
| DC11100 |
PBI-4050 sodium |
PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
|
| DC11099 |
PBI-4050 |
PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
|
| DC11169 |
PCC0104005 |
PCC0104005 (PCC-0104005) is a novel modulator of serotonin, dopamine, and noradrenaline receptors, including partial agonism at dopamine D2, D3, D4, serotonin 5-HT1A, and 5-HT2A receptors and antagonism at 5-HT2B, 5-HT6, and 5-HT7 receptors. |
|
| DC10531 |
PCO371
Featured
|
PCO371 is a novel, orally active small molecule that acts as a full agonist of PTHR1. |
|
| DC7224 |
PD 123319
Featured
|
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. |
|
| DC12316 |
PD-168077 maleate
Featured
|
PD-168077 maleate is a selective dopamine D4 receptor agonist, with a Ki of 9 nM. |
|
| DC9018 |
Pemirolast potassium |
Pemirolast Potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent. |
|
| DC11664 |
PF-00446687 hydrochloride |
PF-00446687 hydrochloride (PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM. |
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