GPCR

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Cat. No.	Product Name	Field of Application
DC5060	(+)PD 128907	(+)PD 128907 is a potent D3 dopamine receptor agonist (Ki = 2.3 nM). Displays 18 - 200-fold selectivity over other dopamine receptor subtypes.
DCAPI1411	Bisoprolol Fumarate Featured	(±)-Bisoprolol hemifumarate is a selective β1-AR adrenergic antagonist. Possesses β1/β2 selectivity of approximately 100-fold and a Kd of 2-3 nM at the β1-AR (β1 receptor).
DC10094	(±)-SLV319(Ibipinabant) Featured	(±)-SLV 319 is a potent and selective CB1 receptor antagonist (Ki = 7.8 nM). Exhibits 1000-fold selectivity for CB1 over CB2 receptors.
DC10160	(1R,2S)-VU0155041	(1R,2S)-VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM.
DC8964	Phenylephrine hydrochloride	(R)-(-)-Phenylephrine hydrochloride is a phenylephrine (PE) and an α1-adrenoceptor agonist
DC11364	Levocetirizine；(R)-Cetirizine (hydrochloride)	(R)-Cetirizine is the (R)-enantiomer of the histamine H1 receptor antagonist and second generation antihistamine cetirizine.
DC9137	Timolol Maleate Featured	(S)-Timolol maleate, is a potent non-selective β-adrenergic receptor antagonist (Ki values are 1.97 and 2.0 nM for β1 and β2 receptor subtypes respectively).
DCZ-156	UR-144	>98%,Standard References
DCZ-059	L-Stepholidine Featured	Stepholidine s a naturally occurring chemical compound found in the herb Stephania intermedia. Stepholidine is a dual D2 receptor antagonist and D1 receptor agonist, and has shown antipsychotic activity in animal studies.
DC10090	4-P-PDOT Featured	4-P-PDOT is a slelctive MT2 melatonin receptor antagonist 300 fold selective for MT2 (MEL-1B-R) vs MT1 (MEL-1A-R) melatonin receptor subtype.
DC10689	4P-PDOT Featured	4P-PDOT, also known as 4-phenyl-2- propionamidotetralin, is a MT2-receptor-specific antagonist. MT2 melatonin receptor may be a novel target for analgesic drug development.
DC10877	5,3-AB-CHMFUPPYCA Featured	5,3-AB-CHMFUPPYCA is an analytical reference standard that is structurally classified as a synthetic cannabinoid.
DC7494	SB-242084 HCl Featured	5-HT2C receptor antagonist that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2Breceptors respectively. Also displays selectivity over a range of other 5-HT, dopamine and adrenergic receptors. Brain penetrant; exerts anxiolytic-like activity.
DC7925	GTPL-5846 (6-OAU) Featured	6-OAU(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.
DC10537	8-OH-DPAT Featured	8-OH-DPAT is a research chemical of the aminotetralin chemical class and has been widely used to study the function of the 5-HT1A receptor.
DC7289	Imiloxan	A moderately potent, but highly selective α2-adrenoceptor antagonist, the only reported selective antagonist at the α2B-adrenoceptor not having potent α1-adrenoceptor antagonist activity.
DCAPI1496	Ambrisentan Featured	A nonpeptide endothelin ETA receptor antagonist. Antihypertensive.
DC11523	Landipirdine	A novel 5-HT receptor antagonist for the treatment of Parkinson's disease..
DC11994	ZQ-16	A novel potent and selective agonist of GPR84 that induces calcium response with EC50 of 0.213 uM.
DC11982	CX815	A novel potent, selective CXCR2 inhibitor with IC50 of 0.4 nM.
DC11981	CX4152	A novel potent, selective CXCR2 inhibitor with IC50 of 7.6 nM.
DC11605	ONO-0300302	A novel potent, slow tight binding LPA1 receptor antagonist with IC50 of 86 nM, Kd of 0.34 nM.
DC11974	L 741742 hydrochloride	A potent and highly selective D4 dopamine receptor antagonist with Ki of 3.5 nM, >200-fold selectivity over D2 and D3 receptors.
DC11743	BMS-681	A potent and orally bioavailable dual antagonist of CCR2 and CCR5 with binding IC50 of 0.7 nM and 2.4 nM, respectively.
DC11705	GPR30 inhibitor G1 Featured	A potent and selective GPER/GPR30 agonist with Ki of 11 nM, EC50 of 2 nM.
DC11699	VUF11403	A potent CXCR7 (ACKR3) agonist..
DC11976	SX-576	A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively.
DC11903	NBUMP	A potent, highly selective 5-HT1A receptor partial agonist with Ki of 0.1 nM, displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively..
DC11609	VU6010608	A potent, highly selective, CNS penetrant mGlu7 negative allosteric modulator with IC50 of 0.76 uM.
DC11758	PB 28 dihydrochloride Featured	A potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively.

GPCR

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