Cat. No. | Product name | CAS No. |
DC48145 |
Besipirdine
Besipirdine is a non-receptor-dependent cholinomimetic agent with noradrenergic activity. Besipirdine inhibits voltage-dependent sodium and potassium channels. |
119257-34-0 |
DC48146 |
KUC-7322
KUC-7322, a selective β3 -adrenoceptor agonist, is the active form of ritobegron. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system. |
255734-04-4 |
DC48147 |
Azilsartan mepixetil
Azilsartan mepixetil is the antagonist of angiotensin II receptor. Azilsartan mepixetil has stronger and longer blood pressure effect, more abvious and longer lasting heart rate lowering effect and high safety. Azilsartan mepixetil achieves ideal protective effect for heart and kidney functions. Azilsartan mepixetil has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy (extracted from patent CN107400122A). |
1596357-16-2 |
DC48148 |
Azilsartan mopivabil
Azilsartan mopivabil is the potent antagonist of angiotensin II receptor. |
2271428-31-8 |
DC48149 |
Mepixetil
Mepixetil is a potent antagonist of angiotensin II receptor. |
|
DC48150 |
Mopivabil
Mopivabil is the antagonist of angiotensin II receptor. |
|
DC48151 |
Deucrictibant
Deucrictibant is a potent bradykinin receptor antagonist. Bradykinin receptors are cell surface, G-protein coupled receptors of the seven-transmembrane domained family. |
2340111-58-0 |
DC48152 |
Vicasinabin
Vicasinabin is the potent agonist of cannabinoid receptor 2 (CB2). Vicasinabin has the potential for the research of human diseases including chronic pain, atherosclerosis, regulation of bone mass, neuroinflammation, and other related diseases (extracted from patent US20130116236A1). |
1433361-02-4 |
DC48153 |
HTL22562
HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine. |
2097085-63-5 |
DC48154 |
SUN B8155
Featured
SUN B8155, a non-peptide agonist of calcitonin (CT) receptor, selectively mimics the biological actions of calcitonin. Calcitonin, a 32-amino acid peptide hormone secreted mainly from the thyroid gland, plays an important role in maintaining bone homeostasis. |
345893-91-6 |
DC48155 |
Sibenadet hydrochloride
Sibenadet hydrochloride (AR-C68397AA) is a dual D2 dopamine receptor, beta2-adrenoceptor agonist with bronchodilator activity. Investigation in animal models of key chronic obstructive pulmonary disease (COPD) symptoms has demonstrated that Sibenadet hydrochloride effectively inhibits sensory nerve activity, thereby reducing reflex cough, mucus production and tachypnoea. |
154189-24-9 |
DC48156 |
Molindone
Molindone ((±)-Molindone), an indole derivative, is a potent dopamine D2 and D5 receptor antagonist. Molindone ((±)-Molindone) can be used for the research of schizophrenia and severe mental illness. |
7416-34-4 |
DC48157 |
Raclopride
Raclopride is a selective dopamine D2/D3 receptor antagonist that discriminates between dopamine-mediated motor functions. Raclopride binds to D2 and D3 receptors with dissociation constants of between 1.8 nM and 3.5 nM, but has a very low affinity for D4 receptors. |
84225-95-6 |
DC48158 |
Utreglutide
Utreglutide is a potent glucagon-like peptide 1 (GLP-1) receptor agonit. |
2460862-12-6 |
DC48159 |
Ecnoglutide
Ecnoglutide is a glucagon-like peptide 1 (GLP-1) receptor agonist. |
2459531-73-6 |
DC48160 |
Masilukast
Masilukast is an orally administered cysteinyl leukotriene D4 (LTD4) receptor antagonist with potential to treat asthma. |
136564-68-6 |
DC48161 |
MK-6884-11C
MK-6884-11C is a positron emission tomography (PET) imaging agent for the study of M4 muscarinic receptor positive allosteric modulators (PAMs) in neurodegenerative diseases. |
|
DC48162 |
Milameline
Milameline is a muscarinic receptor agonist that improves cognition. |
139886-32-1 |
DC48163 |
Sabcomeline hydrochloride
Sabcomeline (hydrochloride) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. |
159912-58-0 |
DC48164 |
Aceclidine
Featured
Aceclidine is a modulator of M3 muscarinic acetylcholine receptor. Aceclidine is a cycloplegic agent, a surfactant, a tonicity adjustor and optionally a viscosity enhancer and an antioxidant. Aceclidine has the potential for the research of disorders such as refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia (extracted from patent US20150290125A1/US20110091459A1). |
827-61-2 |
DC48165 |
Xanomeline tartrate
Xanomeline (LY 246708) is the potent agonist of muscarinic M1/M4 receptor with antipsychotic-like activity. Xanomeline (LY 246708) increases neuronal excitability. Xanomeline (LY 246708) can be used for the research of schizophrenia. |
152854-19-8 |
DC48166 |
Methoctramine tetrahydrochloride
Methoctramine tetrahydrochloride is a potent and cardioselectivity antagonist of M2 muscarinic receptor. Methoctramine tetrahydrochloride can inhibit Muscarine-induced bradycardia in vivo. |
104807-46-7 |