HDAC

You can also try the following methods, and our professionals will serve you Customized Consultation

Cat. No.	Product Name	Field of Application
DC7962	HPOB Featured	HPOB is a novel selective inhibitor of HDAC6 catalytic activity in vivo and in vitro.
DC7487	Pyroxamide Featured	Inhibitor of histone deacetylase (HDAC); potently inhibits affinity purified HDAC1. Also inhibits the growth of tumor cells in vitro and in vivo. Induces p21/WAF1 expression in tumor cells.
DC10220	ITSA-1 (ITSA1) Featured	ITSA-1 (ITSA1) is an HDAC activator via TSA suppression, but shows no activity towards other HDAC inhibitors.
DC4241	LMK-235 Featured	LMK-235 is a selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor (IC50 values are 4.22, 11.9, 55.7, 320, 852, 881, and 1278 nM for HDAC 5, 4, 6, 1, 11, 2, and 8, respectively).
DC5128	MC1568 Featured	MC1568 is a class II (IIa) HDAC inhibitor selective for HDAC4 and HDAC6
DC7196	MGCD0103 (Mocetinostat) Featured	MGCD0103 (Mocetinostat) is a potent HDAC inhibitor with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3, respectively.
DC10063	MPI-5a Featured	MPI_5a is a potent selective inhibitor of HDAC6, and poorly blocks other HDAC enzymes.
DC10951	MPT0E028	MPT0E028 is a potent HDAC inhibitor that inhibits nuclear HDAC activity with IC50 of 11.1 nM in HeLa cells, 9-30 times more potent than SAHA.
DC10938	MPT0G211	MPT0G211 is a novel potent, selective HDAC6 inhibitor with IC50 of 0.291 nM, displays >1,000-fold selectivity over other HDAC isoforms.
DC7548	Nexturastat A Featured	Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM, >190-fold selectivity over other HDACs.
DC7183	Panobinostat(LBH589) Featured	Panobinostat(LBH-589) is a broad-spectrum HDAC inhibitor; low nanomolar concentrations (IC50=5-20 nM) of LBH589 induced cell-cycle arrest, apoptosis, and histone (H3K9 and H4K8) hyperacetylation in MOLT-4 and Reh cell.
DC1109	PCI-34051 Featured	PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM.
DC8661	Pimelic Diphenylamide 106(TC-H 106) Featured	Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I HDAC (HDAC 1, 2, and 3, with IC50 values of 150 nM , 760nM, and 370 nM, respectively), demonstrating no activity against class II HDACs.
DC7280	Pracinostat(SB939) Featured	Pracinostat(SB939) is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with exception for HDAC6; has no activity against the class III isoenzyme SIRT I.
DC8654	PTACH (NCH-51) Featured	PTACH (NCH-51) is a SAHA-based novel inhibitor of human HDAC. PTACH exerts potent growth inhibition against various human cancer cells, with EC50 values ranging from 1 to 10 μM.
DC7176	Quisinostat (JNJ-26481585) 2HCl Featured	Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11.
DC7037	R306465(JNJ-16241199) Featured	R306465, also known as JNJ-16241199, is a novel hydroxamate-based histone deacetylase (HDAC) inhibitor with broad-spectrum antitumour activity against solid and haematological malignancies in preclinical models.
DC8646	Remodelin Featured	Remodelin is an inhibitor of acetyl-transferase NAT10.
DC7796	Remodelin (hydrobromide) Featured	Remodelin is an inhibitor of acetyl-transferase NAT10.
DC7261	Resminostat hydrochloride (4SC-201)	Resminostat(RAS2410; 4SC-201) is a potent inhibitor of HDAC1/3/6(IC50=43-72 nM); less potent to HDAC8 with IC50 of 877 nM.
DC7795	RG2833 (RGFP109) Featured	RG2833 is a brain-penetrant inhibitor of HDAC with IC50 values of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.
DC7263	RGFP 966 Featured	RGFP966 is specific inhibitor of HDAC3, with an IC50 of 0.08 μM and no effective inhibition of any other HDAC at concentrations up to 15 μM.
DC7048	Ricolinostat (ACY-1215) Featured	Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM; >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2.
DCAPI1434	Romidepsin（FK-228） Featured	Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC50 25 nM and 790 nM, respectively.
DC11014	SALL4 peptide FFW Featured	SALL4 peptide FFW (RRKFAKFQWI, FFW peptide) is a potent therapeutic SALL4 peptide antagonist of SALL4-NURD (nucleosome remodeling deacetylase) interaction with target affinity of 23 nM.
DC7284	Scriptaid(GCK1026) Featured	Scriptaid(Scriptide; GCK-1026) is an inhibitor of HDAC; shows a greater effect on acetylated H4 than H3.
DC7673	Splitomicin Featured	Splitomicin is a derivative of β-naphthol is an inhibitor of Silent Information Regulator 2 (SIR2).
DC10788	SR-4370 Featured	SR-4370 is an HDAC inhibitor. SR-4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3, resp.
DC7733	Tasquinimod(ABR-215050) Featured	Tasquinimod is an orally active antiangiogenic agent by allosterically inhibiting HDAC4 signalling.
DC12487	TH-34 Featured	TH34 is a potent HDAC6/8/10 inhibitor, induceing DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.

HDAC

Customized Consultation X

Your information is safe with us. * Required Fields.