| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC8941 | Aclidinium bromide Featured | Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). |
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| DC23795 | ACO1 | ACO1 is a potent, selective Grp94 inhibitor with IC50 of 0.44 uM, displays >200-fold selectivity against other Hsp90 isoforms. |
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| DC7354 | Acolbifene | acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modulator (SERM). Acolbifene is currently being studied in the prevention of breast cancer in women at high risk of breast cancer. EM-652 (SCH 57068) and the prodrug EM-800 ( |
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| DC8798 | Acotiamide Featured | Acotiamide acts as an acetylcholinesterase inhibitor |
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| DC10812 | ACP-105 Featured | ACP-105 is a novel non-steroidal SARM (Selective Androgen Receptor Modulator). |
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| DC10279 | Acrivastine | Acrivastine (BW825C) is a short acting histamine 1 receptor antagonist for the treatment of allergic rhinitis. |
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| DC11512 | Acrizanib Featured | Acrizanib（LHA510） is a potent and selective angiogenesis inhibitor and VEGFR‑2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration. |
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| DC10492 | ACSS2 inhibitor Featured | ACSS2 inhibitor is a novel ACSS2 inhibitor. |
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| DC20640 | ACT 709478 | ACT 709478 is a potent, selective, orally-bioavailable, brain penetrant T-type calcium channel blocker with IC50 of 6.4, 18, and 7.5 nM for Cav3.1, Cav3.2, and Cav3.3 channels respectively. |
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| DC11209 | ACT-246475 | ACT-246475 (ACT246475) is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
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| DC21986 | ACT-281959 | ACT-281959 (ACT281959) is the prodrug of ACT-246475, which is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
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| DC11439 | Nemorexant Featured | ACT-541468 is a dual orexin receptor antagonist. |
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| DC7997 | ACTB-1003 Featured | ACTB-1003 is a potent inhibitor of FGFR1 with IC50 <10 nM in FGFR-1 biochemical assay; more information can be find in Patent WO/2007/064883A2, Example 12. |
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| DC8191 | Sparsentan(PS433540) Featured | Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively[1]. |
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| DC10417 | Acumapimod (BCT197) Featured | Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α. |
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| DC20235 | Ac-WEHD-pNA Featured | Ac-WEAD-pNA is a colorimetric substrate for caspase-1 and caspase-4. |
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| DC8476 | ACY-738 Featured | ACY-738 demonstrates inhibitory activity against recombinant HDAC6 with IC50 values of 1.7 nM, with respective average selectivity over class I HDACs being 100-fold. |
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| DC22659 | ACY-775 | ACY-775 (ACY775) is a potent and specific HDAC6 inhibitor (IC50=7.5 nM) with improved brain bioavailability. |
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| DC11008 | ACY-957 | ACY-957 (ACY957) is a potent, selective inhibitor of HDAC1 and HDAC2 with IC50 of 7 and 18 nM, shows limited activity against HDAC3 (IC50=1,300 nM) and no activity against HDAC4/5/6/7/8/9 (IC50>20 nM). |
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| DCAPI1273 | Acyclovir (Aciclovir) | Acyclovir (Aciclovir) |
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| DC11754 | AD 2900 Featured | AD 2900 (AD2900, AD-2900) is a novel potent, broad S1P receptor antagonist with IC50 of 3.8, 3.2, 6.2, 5.9 and 0.405 uM for S1P1, 2, 3, 4 and 5 respectively. |
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| DC10633 | AD80 Featured | AD80, a multikinase inhibitor, shows strong activity against human RET, BRAF, S6K, and SRC but were much less active than either AD57 or AD58 against mTOR. The IC50 value for RET is 4 nM. |
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| DC20301 | ADAMTS-5 inhibitor 15f | ADAMTS-5 inhibitor 15f is a highly potent and selective inhibitor of metalloprotease ADAMTS-5 with IC50 of 30 nM, >50-fold selectivity against ADAMTS-4 and >1000-fold selectivity against ADAMTS-1/13, MMP-13 and TACE. |
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| DC20302 | ADAMTS-5 inhibitor 8 | ADAMTS-5 inhibitor 8 is a highly potent and selective inhibitor of metalloprotease ADAMTS-5 with IC50 of 30 nM, >50-fold selectivity against ADAMTS-4 and >1000-fold selectivity against ADAMTS-1/13, MMP-13 and TACE. |
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| DCAPI1013 | Adapalene | Adapalene |
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| DC9362 | Adarotene | Adarotene (ST1926) is an effective apoptosis inducer and surprisingly produced DNA damage.ST1926 exhibites a potent antiproliferative activity on a large panel of human tumor cells. IC50 value: 0.12 uM (LNCaP cell) [1] Target: Apoptosis inducer; Antican |
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| DC11886 | Adavivint Featured | Adavivint (SM-04690, SM 04690, SM04690) is a novel small molecule Wnt pathway inhibitor with EC50 of 3 nM in vitro |
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| DC20642 | ADC-3680 | ADC-3680 (PTR-36, ADC-3680B) is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
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| DC21294 | MK-1029 | ADC-3680 is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
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| DC4155 | Adefovir Dipivoxil Featured | Adefovir Dipivoxil(Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. |
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