| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10745 | Adelmidrol Featured | Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid. |
|
| DC10244 | Ademetionine disulfate tosylate | Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. |
|
| DCAPI1268 | Adenosine (Adenocard) | Adenosine (Adenocard) |
|
| DC20163 | Adenosine 5'-monophosphate monohydrate; 5'-Adenylic acid;5'-AMP | Adenosine 5'-monophosphate monohydrate (5'-AMP) is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). |
|
| DC20303 | Adhesamine | Adhesamine is a diaryldispirotripiperazine derivative that selectively targets cell-surface glycosaminoglycans, especially heparan sulfate, for increasing cell adhesion and growth. |
|
| DC10685 | Adipamidoxime(NSC 70868) Featured | Adipamidoxime(NSC 70868) is a new bioactive compoud. |
|
| DCAPI1201 | Adiphenine HCl | Adiphenine HCl |
|
| DC12091 | AdipoRon hydrochloride Featured | AdipoRon hydrochloride is an orally active and specific AdipoR agonist, binding to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM, respectively. |
|
| DC7049 | AdipoRon Featured | AdipoRon is a novel small-molecule AdipoR agonist; binds to both AdipoR1(Kd= 1.8 uM) and AdipoR2(Kd=3.1 uM). |
|
| DC7050 | ADL5859 HCl Featured | ADL5859 agonizes δ-opioid receptor with a 1000-fold selectivity than µ- or κ-opioid receptor with Ki of 32 nM and 37 nM, respectively.ADL5859 displays weak inhibitory activity at the hERG channel with an IC50 of 78 μM. The EC50 of ADL5859 against δ opioid |
|
| DC20644 | ADM 12 | ADM 12 (ADM_12. |
|
| DC9324 | Adoprazine | Adoprazine, a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties. |
|
| DC12115 | Adrenomedullin (AM) (1-52), human TFA (Human adrenomedullin-(1-52)-NH2 (TFA)) | Adrenomedullin (AM) (1-52), human (TFA) affects cell proliferation and angiogenesis in cancer. |
|
| DC20645 | ADT-094 | ADT-094 (ADT094) is a novel, non-COX inhibitory sulindac derivative that potently and selectivity inhibits colon tumor cell growth by inhibiting PDE5 and PDE10 with IC50 of 2.4 uM and 0.5 uM, respectively. |
|
| DC10577 | ADT-OH Featured | ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. |
|
| DC21281 | ADU-S100 Featured | ADU-S100 (MIW815) is a synthetic cyclic dinucleotide agonist of STING, elicits potent and durable anti-tumor immunity when administered IT in pre-clinical syngeneic tumor models.. |
|
| DC11097 | ADX-102 (Reproxalap;NS-2) Featured | ADX-102 (Reproxalap, NS-2) is a novel small molecule immunomodulator that covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal, which have been shown to mediate inflammatory pain; DX-102 is a promising agent for the treatment of dry eye disease. |
|
| DC8087 | ADX 47273 Featured | ADX-47273 is a novel, potent and selective metabotropic glutamate receptor 5 allosteric modulator with an EC50 of 170 nM. |
|
| DC10465 | ADX-88178 Featured | ADX-88178 is a novel potent, selective, and brain-penetrant positive allosteric modulator of the mGlu4 receptor. |
|
| DC7703 | AEBSF-hydrochloride Featured | AEBSF HCl is a broad spectrum, irreversible serine protease inhibitor. |
|
| DC5113 | AEE-788 (NVP-AEE788) Featured | AEE788 is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCα and CDK1. Phase 1/2. |
|
| DC21988 | AER-271 Featured | AER-271 (AER271) is a selective, small molecule inhibitor of aquaporin-4 (AQP4), the prodrug of AER-270 with enhanced solubility. |
|
| DC21989 | AES-135 Featured | AES-135 (AES135) is a novel HDAC inhibitor that biochemically inhibits HDACs 3, 6, 8 and 11 with IC50 values of 190-1100 nM. |
|
| DC8355 | Adjudin (AF-2364) Featured | AF-2364, an analogue of Lonidamine (LND), had a contraceptive effect when orally administered to adult Sprague–Dawley rats. |
|
| DC7783 | AF-353(Ro-4) Featured | AF-353 is a novel, orally bioavailable, highly potent and selective P2X3/P2X2/3 receptor antagonist. |
|
| DC23140 | AF38469 Featured | AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM, shows no activity against the NTR1 receptor as well as a panel of targets known to bind acidic molecules (δ-Opioid, GPR40, PPARδ, EP1, Angiotensin AT1, Endothelin |
|
| DC12539 | AF40431 | AF40431 (AF-40431) is the first reported small-molecule ligand of the VPS10P family sorting receptor Sortilin with IC50 of 4.4 uM, binds in the neurotensin-binding site of sortilin.. |
|
| DC11170 | AF64394 Featured | AF64394 is a potent, selective GPR3 inverse agonist with pIC50 of 7.3, displays >100-fold selectivity over GPR6 and GPR12. |
|
| DC23642 | AF-792 | AF-792 (RO-5) is a novel selective P2X3 and P2X2/3 antagonist with pIC50 of 8.2 and 7.9 respectively, with no inhibition at other P2X receptors. |
|
| DC3164 | BIBW2992-MA2 (Afatinib dimaleate) Featured | Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2. |
|
