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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC7700 AC710 Featured AC710, is a potent Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases.
DC12492 N-(p-Amylcinnamoyl) anthranilic Acid (ACA) Featured ACA is a cell permeable inhibitor of PLA2,reported to inhibit α-ketoisocaproic acid and glyceraldehyde-induced insulin secretion, as well as glucose-induced insulin secretion.
DC9917 Acacetin Featured Acacetin is an O-methylated flavone found in Robinia pseudoacacia (black locust), Turnera diffusa (damiana),Betula pendula (silver birch),and in the fern Asplenium normale.
DC7047 AICAR (Acadesine) Featured Acadesine results in accumulation of ZMP, which mimics the stimulating effect of AMP on AMPK and AMPK kinase. Phase 3.
DC9660 Acalabrutinib(ACP196) Featured Acalabrutinib (ACP-196) is a second-generation, selective, irreversible inhibitor of BTK.
DC8760 Acalisib Featured Acalisib (GS-9820) is a potent and selective inhibitor of PI3Kδ with IC50 value of 12.7 nM.
DC22280 Acarbose Featured Acarbose is the first identified α-glucosidase inhibitor.
DC11458 Ac-DEVD-pNA(Caspase-3 Substrate) Featured Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases.
DC11359 Caspase-3 Substrate Ac-DNLD-AMC is a fluorogenic caspase-3 substrate.
DC9986 Acebilustat(ZK322) Featured Acebilustat(ZK322) is a potent and selective leukotriene A4 hydrolase inhibitor.
DC10592 ASL 601(Acecainide) Featured Acecainide, also known as N-acetylprocainamide and ASL 601, is the N-acetylated metabolite of procainamide.
DC10318 Acelarin Featured Acelarin (NUC-1031) is a ProTide transformation and enhancement of the widely-used nucleoside analogue, gemcitabine.
DC9127 Acemetacin Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
DC9900 Acetaminophen Featured Acetaminophen is a COX inhibitor for COX-1 and COX-2 with IC50 of 113.7 μM and 25.8 μM, respectively.
DCAPI1009 Acetanilide (Antifebrin) Acetanilide (Antifebrin)
DC8978 Acetazolamide Acetazolamide is a potent carbonic anhydrase (CA) inhibitor; best-studied agent for the amelioration of acute mountain sickness (AMS).
DC20115 Acetoacetic acid sodium salt Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes.
DC10248 Acetohydroxamic acid Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.
DC20151 Acetosyringone Featured Acetosyringone is a phenolic compound from wounded plant cells, enables virA gene which encodes a membrane-bound kinase to phosphorylate itself and activate the virG gene product, which stimulates the transcription of other vir genes and itself. Acetosyri
DC12151 Acetyl Perisesaccharide C Acetyl Perisesaccharide C is an oligosaccharide, which is isolated from the root barks of Periploca sepium.
DC9894 Acetylcholine iodide Acetylcholine iodide is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
DC10637 Acetylspiramycin (ASPM) Acetylspiramycin (ASPM) is a macrolide antimicrobial agent.
DC21985 Ac-IEPD-CHO Ac-IEPD-CHO is a potent, reversible inhibitor of serine protease Granzyme B (GzmB) with Ki of 80 nM, also inhibits caspase-7 (Ki=550 nM) and induces apoptosis..
DC11350 Caspase-8 Chromogenic Substrate I Ac-IETD-pNA is a substrate for caspase-8.
DCAPI1205 Acipimox Acipimox
DC1092 Acitazanolast (WP-871,Zepelin) Acitazanolast is an active metabolite of tazanolast and anti-allergic drug.
DCAPI1244 Acitretin Acitretin
DC22805 (R)-9b Ack1 inhibitor (R)-9b is a potent and selective ACK1 (TNK2) inhibitor with IC50 of 48 nM.
DC21864 Ack1 inhibitor 37 Ack1 inhibitor 37 is a potent and selective Ack1 (TNK2) inhibitor with Ki of 0.3 nM, displays high selectivity over related kinases LCK, JAK3, KDR and TIE2 (Ki= 138, 6.5, 380 and 200 nM).
DC11356 Caspase-9 Chromogenic Substrate I Ac-LEHD-pNA is a substrate for caspase-9.1 Caspase-9 preferentially binds to and cleaves the Leu-Glu-His-Asp (LEHD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity.

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