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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC2694 In-1166 Novel ALK5 inhibitor
DCC2695 Incb018424 Racemic Janus-associated kinase (JAK) inhibitor
DCC2696 Incb059872 Tosylate Novel potent and selective lysine-specific demethylase 1 (LSD1) inhibitor
DCC2697 Ind-07 Novel selective Mtb-DHFR inhibitor as an antimycobacterial agent
DCC2698 Ind31119 Novel selective inhibitor of PfHsp90, bypassing its highly similar human orthologs
DCC2699 Ind45193 Antiprion agent, reducing PrP(Sc) levels in dividing and stationary-phase cells
DCC2700 Indazole-cl Selective estrogen receptor modifier (SERM), being a selective ERß agonist
DCC2701 Indeloxazine Hydrochloride Antidepressant and cerebral activator, acting as a serotonin releasing agent, norepinephrine reuptake inhibitor, and NMDA receptor antagonist, enhancing acetylcholine release via activation of the 5-HT4 receptor
DCC2702 Indimitecan Hydrochloride Topoisomerase I (Top1) inhibitor
DCC2703 Indobufen Platelet aggregation inhibitor acting as a reversible Cyclooxygenase>cyclooxygenase inhibitor
DCC2704 Indole-3-lactic Acid Metabolite of tryptophan, reducing the interleukin-8 (IL-8) response after IL-1β stimulus, interacting with the transcription factor aryl hydrocarbon receptor (AHR) and preventing transcription of the inflammatory cytokine IL-8, being anti-inflammatory in
DCC2705 Indolmycin Natural antibiotic, selectively inhibiting bacterial tryptophanyl-tRNA synthetase (TrpRS)
DCC2706 Indoluidin D Novel inhibitor of dihydroorotate dehydrogenase (DHODH), promoting myeloid differentiation and inhibiting the proliferation of acute promyelocytic leukemia HL-60 cells, also suppressing cell growth in various other types of cancer cells
DCC2707 Indotecan Hydrochloride Topoisomerase I (Top1) inhibitor
DCC2708 Indoxam Novel sPLA2 inhibitor, suppressing murine endotoxic shock and LDL modification, blocking binding to the M-type receptor
DCC2709 Indoxyl Sulfate Metabolite of tryptophan, showing adverse effects on bones and the central nervous system, having been most frequently implicated as a contributor to renal disease progression and vascular disease
DCC2710 Infraluciferin NIR emitting firefly luciferin analogue
DCC2711 Ingavirin Novel inhibitor of the influenza virus reproduction, inhubiting the formation of the virus specific hemagglutinin
DCC2712 inh-32 Novel inhibitor of Ark1, the fission yeast member of the conserved Aurora kinase family
DCC2713 Inhib1x Novel dual inhibitor of MAPKAPK5 and MAPKAPK2
DCC2714 Inhibitor R1 Novel Potent Inhibitor of Microbiome ß-Glucuronidases
DCC2715 Inhibitor R3 Novel Potent Inhibitor of Microbiome ß-Glucuronidases
DCC2716 Inos-in-10 Novel selective inhibitor of the iNOS, without affecting the eNOS isoform
DCC2717 Inos-in-18 Novel Potent and Selective Inducible Nitric Oxide Synthase (iNOS) Inhibitor (IC50 = 74 nM) with high BBB permeability (Pe = 19.1 × 10-6 cm/s) for Parkinson's Disease
DCC2718 Inos-in-d27 Novel Potent and Orally Active Inducible Nitric Oxide Synthase (iNOS) Dimerization Inhibitor with Efficacy in Rheumatoid Arthritis Mouse Model
DCC2719 Inp1750 Novel putative inhibitor of type III secretion (T3S) in the Gram-negative pathogen Yersinia pseudotuberculosis and Chlamydia trachomatis
DCC2720 Ins015_037 Novel potent inhibitor of DDR1 tyrosine kinase
DCC2721 Ins3-54-a26 Novel inhibitor of the DNA-binding domain (DBD) of STAT3, suppressing tumor growth, metastasis and STAT3 target gene expression in vivo
DCC2722 Ins48823 Activator of the P2Y6 receptor in bone, increasing survival of osteoclasts
DCC2723 Int2-31 Blocker of the interaction of FAK and IGF-1R; Antagonist of the phosphorylation of tumor AKT

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