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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC2724 Intervenolin Natural potent inhibitor of H. pylori DHODH, having greater efficacy for treatment of H. pylori infection
DCC2725 Intoplicine Inhibitor of both topoisomerase I and II via intercalating DNA helix
DCC2726 Inuloxin A Natural Activator of Programmed Cell Death, leading to membrane damage, mitochondria alteration, chromatin condensation, and ROS accumulation
DCC2727 Inz-4 [1585213-98-4] Novel Potent Fungal-Selective Inhibitor of Mitochondrial Cytochrome bc1
DCC2728 Iodiconazole Novel antifungal agent, exhibiting broad spectrum and potent activity against 12 kinds of clinically pathogenic fungi
DCC2729 Iodoclorgyline Selective monoamine oxidase A inhibitor
DCC2730 Ipcs-1 Novel inhibitor of the plant inositol phosphorylceramide synthase ((IPCS), demonstrating herbicidal activity
DCC2731 Iperoxo-bqca C6 Muscarinic Acetylcholine Receptor Hybrid Ligand, possessing noticeable M2/M4 mAChR selectivity
DCC2732 Ipi-269609 Orally bioavailable inhibitor of Hedgehog signaling, inhibiting tumor initiation and metastasis in pancreatic cancer
DCC2733 Ipomeamarone Natural toxic furanoterpenoid found in mold-damaged sweet potatoes
DCC2734 Ipomoeassin F Natural inhibitor of the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor, binding Sec61α to Inhibit Protein Translocation
DCC2735 Ipr-2025 Novel inhibitor of glioblastoma multiforme (GBM), inhibiting cell viability of low-passage patient-derived GBM spheroids, blocking tube-formation of endothelial cells in Matrigel, showing no effect on primary hematopoietic CD34+ progenitor spheroids or as
DCC2736 ipr-456 Inhibitor of the uPAR·uPA protein-protein interaction, blocking cancer cell invasion
DCC2737 Iproclozide Irreversible and nonselective Monoamine_oxidase_inhibitor>monoamine oxidase inhibitor (MAOI)
DCC2738 Ips-02001 Novel inhibitor of protein-protein interaction (PPI), targeting integrin αvβ3-osteopontin interface, blocking OC maturation from murine bone marrow-derived macrophages, as well as the resorptive function of OCs, impairing downstream signaling of integrin
DCC2739 Ipsalazide Sulfasalazine analog, releasing 5-aminosalicylic acid and a nontoxic carrier molecule in the gastrointestinal tract
DCC2740 Iqs-01.01rs Novel potent inverse agonist of the chemokine receptor CXCR4, preventing CXCL12-mediated chemotaxis and triggering apoptosis in a panel of 18 cell lines and primary cultures, with superior mobilizing properties in vivo
DCC2741 Ir-1061 NIR-II cyanine dye for cancer treatment and diagnosis
DCC2742 Irak Inhibitor 3 Novel interleukin-1 (IL-I) receptor-associated kinase (IRAK) modulator
DCC2743 Irak3 Degrader 23 Novel potent and selective degrader of IRAK3, inducing proteasome-dependent degradation of IRAK3 and showing both CRBN and IRAK3 binding for activity
DCC2744 Irak4-in-13 Novel Orally Efficacious IRAK4 Inhibitor, Targeting MyD88L265P Mutant Diffuse Large B Cell Lymphoma
DCC2745 Irc-083864 Novel inhibitor of CDC25 phosphatases, actively against human cancer cells
DCC2746 ire1-in-vii Inhibitor of IRE1 endoribonuclease activity, strongly inhibiting XBP-1 splicing in an in vivo model of acute endoplasmic reticulum stress.
DCC2747 Irl-1620 ET B receptor agonist, showing anti-apoptotic activity and protecting neural cells in rats with cerebral ischemia
DCC2748 Isam-c032 Novel potent hA2BAR antagonist (Ki = 3.66 nM)
DCC2749 Isatin-o Neutral BBB crossing reactivator for acetylcholinesterase inhibited by paraoxon, also acting as anticonvulsant
DCC2750 Isbogrel Selective thromboxane A2 (TXA2) synthase inhibitor
DCC2751 Isir-005 Natural Stabilizer of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface
DCC2752 Iso-dehydrozingerone Novel osteoclastogenesis inhibitor, preventing ovariectomy-induced osteoporosis in ddY mice
DCC2753 Isofagomine Iminosugar, binding selectively to N370S glucocerebrosidase and restoring its correct conformation and, consequently, enhancing its activity

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