DCC2724 |
Intervenolin |
Natural potent inhibitor of H. pylori DHODH, having greater efficacy for treatment of H. pylori infection |
|
DCC2725 |
Intoplicine |
Inhibitor of both topoisomerase I and II via intercalating DNA helix |
|
DCC2726 |
Inuloxin A |
Natural Activator of Programmed Cell Death, leading to membrane damage, mitochondria alteration, chromatin condensation, and ROS accumulation |
|
DCC2727 |
Inz-4 [1585213-98-4] |
Novel Potent Fungal-Selective Inhibitor of Mitochondrial Cytochrome bc1 |
|
DCC2728 |
Iodiconazole |
Novel antifungal agent, exhibiting broad spectrum and potent activity against 12 kinds of clinically pathogenic fungi |
|
DCC2729 |
Iodoclorgyline |
Selective monoamine oxidase A inhibitor |
|
DCC2730 |
Ipcs-1 |
Novel inhibitor of the plant inositol phosphorylceramide synthase ((IPCS), demonstrating herbicidal activity |
|
DCC2731 |
Iperoxo-bqca C6 |
Muscarinic Acetylcholine Receptor Hybrid Ligand, possessing noticeable M2/M4 mAChR selectivity |
|
DCC2732 |
Ipi-269609 |
Orally bioavailable inhibitor of Hedgehog signaling, inhibiting tumor initiation and metastasis in pancreatic cancer |
|
DCC2733 |
Ipomeamarone |
Natural toxic furanoterpenoid found in mold-damaged sweet potatoes |
|
DCC2734 |
Ipomoeassin F |
Natural inhibitor of the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor, binding Sec61α to Inhibit Protein Translocation |
|
DCC2735 |
Ipr-2025 |
Novel inhibitor of glioblastoma multiforme (GBM), inhibiting cell viability of low-passage patient-derived GBM spheroids, blocking tube-formation of endothelial cells in Matrigel, showing no effect on primary hematopoietic CD34+ progenitor spheroids or as |
|
DCC2736 |
ipr-456 |
Inhibitor of the uPAR·uPA protein-protein interaction, blocking cancer cell invasion |
|
DCC2737 |
Iproclozide |
Irreversible and nonselective Monoamine_oxidase_inhibitor>monoamine oxidase inhibitor (MAOI) |
|
DCC2738 |
Ips-02001 |
Novel inhibitor of protein-protein interaction (PPI), targeting integrin αvβ3-osteopontin interface, blocking OC maturation from murine bone marrow-derived macrophages, as well as the resorptive function of OCs, impairing downstream signaling of integrin |
|
DCC2739 |
Ipsalazide |
Sulfasalazine analog, releasing 5-aminosalicylic acid and a nontoxic carrier molecule in the gastrointestinal tract |
|
DCC2740 |
Iqs-01.01rs |
Novel potent inverse agonist of the chemokine receptor CXCR4, preventing CXCL12-mediated chemotaxis and triggering apoptosis in a panel of 18 cell lines and primary cultures, with superior mobilizing properties in vivo |
|
DCC2741 |
Ir-1061 |
NIR-II cyanine dye for cancer treatment and diagnosis |
|
DCC2742 |
Irak Inhibitor 3 |
Novel interleukin-1 (IL-I) receptor-associated kinase (IRAK) modulator |
|
DCC2743 |
Irak3 Degrader 23 |
Novel potent and selective degrader of IRAK3, inducing proteasome-dependent degradation of IRAK3 and showing both CRBN and IRAK3 binding for activity |
|
DCC2744 |
Irak4-in-13 |
Novel Orally Efficacious IRAK4 Inhibitor, Targeting MyD88L265P Mutant Diffuse Large B Cell Lymphoma |
|
DCC2745 |
Irc-083864 |
Novel inhibitor of CDC25 phosphatases, actively against human cancer cells |
|
DCC2746 |
ire1-in-vii |
Inhibitor of IRE1 endoribonuclease activity, strongly inhibiting XBP-1 splicing in an in vivo model of acute endoplasmic reticulum stress. |
|
DCC2747 |
Irl-1620 |
ET B receptor agonist, showing anti-apoptotic activity and protecting neural cells in rats with cerebral ischemia |
|
DCC2748 |
Isam-c032 |
Novel potent hA2BAR antagonist (Ki = 3.66 nM) |
|
DCC2749 |
Isatin-o |
Neutral BBB crossing reactivator for acetylcholinesterase inhibited by paraoxon, also acting as anticonvulsant |
|
DCC2750 |
Isbogrel |
Selective thromboxane A2 (TXA2) synthase inhibitor |
|
DCC2751 |
Isir-005 |
Natural Stabilizer of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface |
|
DCC2752 |
Iso-dehydrozingerone |
Novel osteoclastogenesis inhibitor, preventing ovariectomy-induced osteoporosis in ddY mice |
|
DCC2753 |
Isofagomine |
Iminosugar, binding selectively to N370S glucocerebrosidase and restoring its correct conformation and, consequently, enhancing its activity |
|