| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCC2784 | Jak1-in-38a | Novel highly potent JAK1-selective inhibitor, exhibiting excellent selectivity over JAK2, JAK3, and TYK2 (IC 50 : JAK1 0.145 nM; JAK2 2.94 nM; JAK3 2.31 nM; TYK2 8.17 nM) |
|
| DCC2785 | Jak1-in-b61 | Novel JAK1 inhibitor |
|
| DCC2786 | Jak2-in-7j | Novel selective Jak2 inhibitor, demonstrating a time-dependent knock-down of pSTAT5, a downstream target of Jak2 |
|
| DCC2787 | Jak3-in Tricyclic-1 | Novel irreversible selective JAK3 inhibitor through the covalent interaction with a Jak3 active-site cysteine |
|
| DCC2788 | Jak3-in Tricyclic-2 | Novel irreversible selective JAK3 inhibitor through the covalent interaction with a Jak3 active-site cysteine |
|
| DCC2789 | Jak3-in Tricyclic-3 | Novel irreversible selective JAK3 inhibitor through the covalent interaction with a Jak3 active-site cysteine |
|
| DCC2790 | Jak3-in-4 | Novel Selective JAK3 Inhibitor with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket |
|
| DCC2791 | Jak3-in-5 | Novel Selective JAK3 Inhibitor with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket |
|
| DCC2792 | Jak-in-1 | Novel potent JAK1/2/3 inhibitor |
|
| DCC2793 | Jak-in-3 | Novel potent JAK1/3 inhibitor, targeting JAK3 and JAK1 with IC 50 at 3nM and 5nM, respectively |
|
| DCC2794 | Jami1001a | Novel positive allosteric modulator of AMPA receptor |
|
| DCC2795 | Jamunone M | Novel anti-triple-negative breast cancer (anti-TNBC) agent with a high selectivity against BC cells over normal human cells, downregulating phosphatidylinositide 3-kinase (PI3K)/Akt pathway by suppressing protein-tyrosine phosphatase 1B (PTP1B) expression |
|
| DCC2796 | Janelia Fluor 526, Se | Novel fluorogenic yellow fluorescent dye for use in self-labeling tag systems |
|
| DCC2797 | Jar1.39 | Novel mitophagy inducer with therapeutic potential for Parkinson's disease, acting as light chain 3 (LC3) interactors, similar to cardiolipin or ceramide, triggering mitophagy via Pink1/Parkin |
|
| DCC2798 | jarid1b Demethylase Inhibitor | Novel Inhibitor of Jumonji AT-Rich Interactive Domain 1B (JARID1B) Histone Demethylase |
|
| DCC2799 | Jasminine | Natural naphthyridine alkaloid |
|
| DCC2800 | Jasplakinolide | Potent inhibitor of the proliferation of PC3 prostate carcinoma cells |
|
| DCC2801 | Jbir-22 | Natural Inhibitor for Protein−Protein Interaction of the Homodimer of Proteasome Assembly Factor 3 |
|
| DCC2802 | Jbir-59 | Natural radical scavenger, inhibiting L-glutamate toxicity in neuronal hybridoma N18-RE-105 cells |
|
| DCC2803 | Jbp485 | Inhibitor of renal transporters OAT1 and OAT3; Antihepatitis agent as a substrate for intestinal PEPT1 |
|
| DCC2804 | Jbp923 | Natural anti-inflammatory agent, showing potential for the treatment of inflammatory bowel disease (IBD) |
|
| DCC2805 | Jbsnf-000567 | Metabolite of JBSNF-000088 |
|
| DCC2806 | Jc1-40 | Novel RORα activator, diminishing diethylnitrosamine-induced acute liver injury and repressing transcriptional expression of APPs such as CXCL1 and LCN2 in mice |
|
| DCC2807 | Jcp-170 | Novel dose-dependent inhibitor of ABHD6 |
|
| DCC2808 | jcp174-alk | JCP174 analog used for affinity purification of labeled targets |
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| DCC2809 | jcp174-ia | Negative control of JCP174 |
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| DCC2810 | Jcp-265 | Novel dose-dependent inhibitor of ABHD6 |
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| DCC2811 | Jcp405 | Covalent dual inhibitor of DPAP1 and DPAP3 |
|
| DCC2812 | Jcp410 | Covalent dual inhibitor of DPAP1 and DPAP3 |
|
| DCC2813 | Jcp474 | Novel potent inhibitor of Mpro |
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