DCC2754 |
Isomazole |
Potent inotropic agent, inhibiting both PDE3 and PDE4 |
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DCC2755 |
Isomyristicin |
Natural essential oil, showing activity against T. muris |
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DCC2756 |
Isopedopeptin B |
Natural antibacterial agent with cytotoxicity and hemolytic properties against a larger panel of Gram-negative bacteria |
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DCC2757 |
Iso-ppads |
P2X-purinoceptor antagonist |
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DCC2758 |
Isowighteone |
Natural genistein derivetive with antibacterial and antifungal activities |
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DCC2759 |
Isoxaben |
Inhibitor of the cellulose biosynthesis, inhibiting anisotropic cell expansion resulting in a severely swollen and stunted growth phenotype |
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DCC2760 |
Isox-inact |
Biological Active Reagents |
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DCC2761 |
Isph Inhibitor 23.20-tpp |
Novel prodrug of potent IspH inhibitor, killing clinical isolates of several multidrug-resistant bacteria, including those from the genera Acinetobacter, Pseudomonas, Klebsiella, Enterobacter, Vibrio, Shigella, Salmonella, Yersinia, Mycobacterium and Baci |
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DCC2762 |
Isp-vt |
Novel inhibitor of COX and neutrophil migration |
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DCC2763 |
Isq-1 Hydrochloride |
Distinct IKur blocker |
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DCC2764 |
Ist-622 |
Unique topoisomerase inhibitor, showing significant growth-inhibitory effects against large-cell lung cancer (Lu-116) and gastric adenocarcinoma (St-4) |
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DCC2765 |
Isvy130 |
Novel Potent and Selective A3 Antagonist |
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DCC2766 |
Ite-atra |
Novel degrader of CRABP proteins |
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DCC2767 |
Ite-conhch3 |
Novel highly potent (EC 50 = 1.6 nM) aryl hydrocarbon receptor (AhR) agonist with high affinity (K i = 88 nM) |
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DCC2768 |
Itf3756 |
Novel Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitor, showing a remarkably low toxicity both in vitro and in vivo and increasing the function of regulatory T cells (Tregs) at well-tolerated concentrations |
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DCC2769 |
Itf3985 |
Novel selective HDAC6 inhibitor |
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DCC2770 |
ith12246 |
Novel PP2A ligand, protecting against memory impairment and focal cerebral ischemia in mice |
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DCC2771 |
Ith12505 |
Novel neuroprotective agent |
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DCC2772 |
Ith15004 |
Novel, potent, selective, and BBB-permeable P2X7 antagonist |
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DCC2773 |
Itx-4520 |
Novel highly potent, orally bioavailable hepatitis C virus (HCV) entry inhibitor |
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DCC2774 |
Ityr-dbrmd |
First-in-class iodothyronine deiodinase type 3 (DIO3) inhibitor, demonstratig attenuated cell counts, induction in apoptosis, and a reduction in cell proliferation in DIO3-positive HGSOC cells (OVCAR3 and KURAMOCHI) |
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DCC2775 |
Ivabradine |
Selective inhibitor of the funny channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the myocardium |
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DCC2776 |
Ivde77 |
The first Ang IV-analogue being able to abolish IRAP-availability completely at the cell surface in vitro |
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DCC2777 |
Ivq Hydrochloride |
Prodrug of QVO, being quickly converted to QVO in mice and rats following administration, ameliorating hyperglycemia, and suppressing hepatic gluconeogenesis and activating AMPK signaling pathway in the liver tissues |
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DCC2778 |
Iwp-051 |
Novel, orally available soluble guanylate cyclase (sGC) stimulator with once-daily dosing potential for the treatment of cardiovascular diseases |
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DCC2779 |
Iwp2g9 |
Novel WNT inhibitor, suppressing cytoplasmic and nuclear biochemical markers of WNT signaling in cultured cells, inhibiting recombinant TNKS activity, or WNT fatty acylation |
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DCC2780 |
Iwr107 |
Novel WNT inhibitor, suppressing cytoplasmic and nuclear biochemical markers of WNT signaling in cultured cells, inhibiting recombinant TNKS activity, or WNT fatty acylation |
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DCC2781 |
Iy-iy-das |
Novel potent noncleavable proteolysis targeting chimeric (PROTAC) for TrkC degradation in metastatic breast cancer cells |
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DCC2782 |
Iy-iy-ss-das |
Novel potent and cleavable proteolysis targeting chimeric (PROTAC) for TrkC degradation in metastatic breast cancer cells |
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DCC2783 |
J-2156 Tfa Salt |
Potent and selective agonist of human somatostatin receptor 4 (sst4), reducing mechanosensitivity of peripheral nerve afferents and spinal neurons in an inflammatory pain model |
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