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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC2754 Isomazole Potent inotropic agent, inhibiting both PDE3 and PDE4
DCC2755 Isomyristicin Natural essential oil, showing activity against T. muris
DCC2756 Isopedopeptin B Natural antibacterial agent with cytotoxicity and hemolytic properties against a larger panel of Gram-negative bacteria
DCC2757 Iso-ppads P2X-purinoceptor antagonist
DCC2758 Isowighteone Natural genistein derivetive with antibacterial and antifungal activities
DCC2759 Isoxaben Inhibitor of the cellulose biosynthesis, inhibiting anisotropic cell expansion resulting in a severely swollen and stunted growth phenotype
DCC2760 Isox-inact Biological Active Reagents
DCC2761 Isph Inhibitor 23.20-tpp Novel prodrug of potent IspH inhibitor, killing clinical isolates of several multidrug-resistant bacteria, including those from the genera Acinetobacter, Pseudomonas, Klebsiella, Enterobacter, Vibrio, Shigella, Salmonella, Yersinia, Mycobacterium and Baci
DCC2762 Isp-vt Novel inhibitor of COX and neutrophil migration
DCC2763 Isq-1 Hydrochloride Distinct IKur blocker
DCC2764 Ist-622 Unique topoisomerase inhibitor, showing significant growth-inhibitory effects against large-cell lung cancer (Lu-116) and gastric adenocarcinoma (St-4)
DCC2765 Isvy130 Novel Potent and Selective A3 Antagonist
DCC2766 Ite-atra Novel degrader of CRABP proteins
DCC2767 Ite-conhch3 Novel highly potent (EC 50 = 1.6 nM) aryl hydrocarbon receptor (AhR) agonist with high affinity (K i = 88 nM)
DCC2768 Itf3756 Novel Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitor, showing a remarkably low toxicity both in vitro and in vivo and increasing the function of regulatory T cells (Tregs) at well-tolerated concentrations
DCC2769 Itf3985 Novel selective HDAC6 inhibitor
DCC2770 ith12246 Novel PP2A ligand, protecting against memory impairment and focal cerebral ischemia in mice
DCC2771 Ith12505 Novel neuroprotective agent
DCC2772 Ith15004 Novel, potent, selective, and BBB-permeable P2X7 antagonist
DCC2773 Itx-4520 Novel highly potent, orally bioavailable hepatitis C virus (HCV) entry inhibitor
DCC2774 Ityr-dbrmd First-in-class iodothyronine deiodinase type 3 (DIO3) inhibitor, demonstratig attenuated cell counts, induction in apoptosis, and a reduction in cell proliferation in DIO3-positive HGSOC cells (OVCAR3 and KURAMOCHI)
DCC2775 Ivabradine Selective inhibitor of the funny channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the myocardium
DCC2776 Ivde77 The first Ang IV-analogue being able to abolish IRAP-availability completely at the cell surface in vitro
DCC2777 Ivq Hydrochloride Prodrug of QVO, being quickly converted to QVO in mice and rats following administration, ameliorating hyperglycemia, and suppressing hepatic gluconeogenesis and activating AMPK signaling pathway in the liver tissues
DCC2778 Iwp-051 Novel, orally available soluble guanylate cyclase (sGC) stimulator with once-daily dosing potential for the treatment of cardiovascular diseases
DCC2779 Iwp2g9 Novel WNT inhibitor, suppressing cytoplasmic and nuclear biochemical markers of WNT signaling in cultured cells, inhibiting recombinant TNKS activity, or WNT fatty acylation
DCC2780 Iwr107 Novel WNT inhibitor, suppressing cytoplasmic and nuclear biochemical markers of WNT signaling in cultured cells, inhibiting recombinant TNKS activity, or WNT fatty acylation
DCC2781 Iy-iy-das Novel potent noncleavable proteolysis targeting chimeric (PROTAC) for TrkC degradation in metastatic breast cancer cells
DCC2782 Iy-iy-ss-das Novel potent and cleavable proteolysis targeting chimeric (PROTAC) for TrkC degradation in metastatic breast cancer cells
DCC2783 J-2156 Tfa Salt Potent and selective agonist of human somatostatin receptor 4 (sst4), reducing mechanosensitivity of peripheral nerve afferents and spinal neurons in an inflammatory pain model

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