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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC2844 Jnj-40929837 Novel potent, orally active LTA4H inhibitor
DCC2845 Jnj-42396302 Novel inhibitor of PDE10A
DCC2846 Jnj-42491293 Novel ago-PAM for the metabotropic glutamate receptor subtype 2 (mGluR2)
DCC2847 Jnj-49153390 Novel inhibitor of respiratory syncytial virus (RSV), binding the RSV F glycoprotein and inhibiting membrane fusion
DCC2848 Jnj-53721590 Negative control for JNJ-54119936
DCC2849 Jnj-61432059 Novel TARP γ-8 Selective AMPAR Negative Modulator
DCC2850 Jnj-dgat1-a Selective DGAT1 inhibitor
DCC2851 Jnj-dgat2-b Selective DGAT2 inhibitor
DCC2852 Jns 1-40 Novel cysteine-reactive covalent ligand, selectively targeting C377 of PPP2R1A to impair breast cancer signaling, proliferation, and in vivo tumor growth
DCC2853 Jp1201 Novel SMAC mimetic, sensitizing non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner
DCC2854 Jp4-039 Non-toxic radioprotector GS-nitroxide, improving hematopoiesis in long-term bone marrow cultures (LTBMCs)
DCC2855 Jr-220 Non-toxic anti-relapse agent, acamprosate
DCC2856 Jra-003 Novel selective inhibitor of nuclear translocation of IKKα as the most potent synthetic gibberellin against cancer-derived cell lines, displaying no cytotoxicity in cells derived from noncancerous sources (HEK 293T, HS 578BST, HS 888Lu, HS 895Sk, HUVEC)
DCC2857 Jrc-ii-191 Novel inhibitor of CD4-gp120 binding, blocking the binding of the HIV-1 envelope glycoprotein gp120 to the CD4 receptor
DCC2858 Js399-19 Novel specific inhibitor of Fusarium myosin I; Fungicide
DCC2859 Jsf-2019 Novel antitubercular agent, inhibiting InhA and FAS-II pathway
DCC2860 Jsf-2513 Novel potent antitubercular agent, inhibiting InhA and FAS-II pathway
DCC2861 Jsi287 Novel ERK inhibitor, alleviating IMQ-induced mice skin lesions through ERK/IL-17 signaling pathway
DCC2862 Jte-151 Novel RORγ
DCC2863 Jte-607 Cytokine release inhibitor, inhibiting production of IL-1ß, IL-8, IL-6, IL-10 and TNFalpha
DCC2864 Jtk-853 Novel nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase
DCC2865 Jts-653 Novel orally active and selective transient receptor potential vanilloid 1 (TRPV1) antagonist
DCC2866 Jtt-552 Novel inhibitor of urate transporter 1 (URAT1)
DCC2867 jtv-506 Novel K(ATP) channel opener
DCC2868 Jtv-803 Mesylate Specific inhibitor of factor Xa
DCC2869 Julolidine Phenoxazone Azide Novel live-cell peobe of voltage-dependent structural changes of voltage-gated Kv2.1 channels
DCC2870 jwb1-84-1 Trihydrochloride Novel neuroprotective agent, improving cognitive performances in a transgenic mouse model of AD
DCC2871 Jwg-115 Novel BET selective inhibitor, targeting BRD4
DCC2872 Jwh-007 Potent cannabinoid (CB) receptor agonist
DCC2873 Jwu-a021 Novel potent stimulator of glucagon-like peptide-1 (GLP-1) secretion in vitro, also potently stimulating Ca(2+) influx through TRPA1 cation channels, being one of the most potent non-electrophilic TRPA-1 channel agonists

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