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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC2979 kv1.5-in-iiii Potent Kv1.5 inhibitor
DCC2980 Kv2.1/syntaxin-in-cpd5 Novel neuroprotectant, inhibiting Kv2.1-syntaxin molecular interaction
DCC2981 Kva-d-88 Novel Preferable Phosphodiesterase 4B (PDE4B) Inhibitor, Decreasing Cocaine-Mediated Reward Properties in Vivo
DCC2982 Ky1022 Ras destabilizer, targeting the Wnt/ß-catenin pathway and inhibiting development of metastatic colorectal cancer
DCC2983 Kya1797 Novel inhibitor of the Wnt/ß-catenin pathway, binding directly to the regulators of G-protein signaling domain of axin, initiating ß-catenin and Ras degradation through enhancement of the ß-catenin destruction complex activating GSK3ß, effectively suppres
DCC2984 Kys05047 Selective T-type Ca(2+) channel blocker with anti-proliferative effects against various cancer cells
DCC2985 L-161240 Potent inhibitor of LpxC and lipid A biosynthesis
DCC2986 L-162782 Nonpeptide agonist of angiotensin AT1 receptor
DCC2987 L17er4 Novel cell-permeable attenuated cationic amphiphilic lytic (ACAL) peptide, efficiently bring immunoglobulin G (IgG) and other functional proteins into cells
DCC2988 L2-4048 Novel Migration Inhibitory Factor (MIF) inhibitor, binding at the allosteric and tautomerase sites, blocking MIF's tautomerase CD74 receptor binding, and pro-inflammatory activities
DCC2989 L458-bpyne Novel γ-secretase modulator photoaffinity probe, identifying distinct allosteric binding sites on presenilin that can be exploited to reduce levels of pathogenic Aβ species
DCC2990 L465046 (α-synuclein Amyloid Aggregation Inhibitor) Novel inhibitor of α-synuclein amyloid aggregation for the treatment of Parkinson's disease
DCC2991 L524-0366 Novel inhibitor of the TWEAK-Fn14 signaling cascade
DCC2992 L61h46 Novel potent inhibitor of human pancreatic cancer cells
DCC2993 L-651392 Potent leukotriene inhibitor
DCC2994 L-658758 Blocker of the activity of human neutrophil elastase (NE), human proteinase-3, human macrophage metalloelastase, mouse macrophage metalloelastase and Pseudomonas aeruginosa elastase
DCC2995 L-663581 Novel partial agonist of the benzodiazepine receptor
DCC2996 L-680833 Potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase (PMNL-E)
DCC2997 L-682679 HIV protease inhibitor
DCC2998 L-687306 Novel partial agonist of muscarinic M1 receptors
DCC2999 L-696229 HIV-1 non-nucleoside reverse transcriptase inhibitor
DCC3000 L-708906 Inhibitor of Human Immunodeficiency Virus Type 1 (HIV-1)
DCC3001 L-731988 Inhibitor of Strand Transfer, Preventing Integration and Inhibiting HIV-1 Replication in Cells
DCC3002 L-735821 Inhibitor of the KCNQ1 channel
DCC3003 L-739758 Potent glycoprotein IIb/IIIa inhibitor
DCC3004 L-744832 Ras farnesyltransferase inhibitor, inhibiting in p70(s6k) phosphorylation in mammary tumors, inducing tumor regression in transgenic mice by mediating alterations in both cell cycle control and apoptosis
DCC3005 L-749329 Dual ET(A)/ET(B) endothelin receptor antagonist
DCC3006 L-768673 Class III antiarrhythmic agent, selectively blocking the slowly activating cardiac delayed rectifier potassium current Iks
DCC3007 L-770644 Potent and selective agonist of the human beta3 adrenergic receptor
DCC3008 L-778123 Featured L-778123 is a dual FPTase and GGPTase-I inhibitor, with IC50s of 2 nM and 98 nM respectively.

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