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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC3114 lm-24 Hydrochloride Novel p75NTR antagonist
DCC3115 lmc-21 Novel AI-2 quorum-sensing inhibitor, affecting the starvation response and reducing virulence in several Vibrio species, most likely by interfering with LuxPQ
DCC3116 Lmptp-in-5d Novel highly selective inhibitor of the low-molecular-weight protein tyrosine phosphatase (LMPTP), being highly orally bioavailable and reversing obesity-induced diabetes in mice
DCC3117 Ln3844 Novel Two-in-One Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites
DCC3118 lnp-509 Potent and selective ligand of imidazoline 1 receptor (I 1 R)
DCC3119 Lnp599 Hydrochloride Novel potent and specific agonist of I 1 imidazoline receptors
DCC3120 Lobeglitazone Sulfate Featured Peroxisome proliferator-activated receptor-α/γ (PPAR α/γ) dual agonist
DCC3121 Lobelane Hydrochloride Inhibitor of the Vesicular_monoamine_transporter_2>vesicular monoamine transporter-2 (VMAT2)
DCC3122 Lomefloxacin Antibiotic for treatment of bacterial infections including bronchitis and urinary tract infections, prevent urinary tract infections prior to surgery
DCC3123 Longanlactone Natural neurotrophic agent
DCC3124 Loperamide Opioid receptor agonist, acting on the µ-opioid receptors in the myenteric plexus of the large intestine
DCC3125 Lopinavir M-3/m-4 Lopinavir Secondary Metabolite
DCC3126 Lox-activity Sensor-1 Novel LOX-activity sensor for cross-linking with a collagen peptide to chemoselectively target endogenous aldehydes generated by LOX
DCC3127 Lp-20 Hydrochloride Potent ligand of the 5-HT7 receptor
DCC3128 Lp-261 Potent antimitotic and oral tubulin binding agent, significantly inhibiting growth of a human non-small-cell lung tumor
DCC3129 Lp-922761 Novel potent and selective peripheral AAK1 inhibitor
DCC3130 Lp-925219 Novel inhibitor of both renal SGLT1 and SGLT2
DCC3131 Lpa1-3 Agonist Cpx Novel LPA 1-3 agonist, inducing a calcium response in hLPA 1-3 cells within a range of 0.4 to 1.5-log lower potency, as compared to LPA
DCC3132 Lpa1-3 Agonist Cpy Novel LPA 1-3 agonist, inducing a calcium response in hLPA 1-3 cells within a range of 0.4 to 1.5-log lower potency, as compared to LPA
DCC3133 Lqfm030 Novel p53 activator through the inhibition of MDM2
DCC3134 Lqmed 330 Novel potent and specific inhibitor of O-linked β-N-acetylglucosamine transferase (OGT)
DCC3135 Lrh-1 Agonist 10ca Novel agonist of liver receptor homolog-1 (LRH-1), reducing the expression of lipogenic genes in mouse liver, and inflammation and disease severity in a mouse model of ulcerative colitis
DCC3136 Lrh-1 Agonist-6n Novel potent agonist of the liver receptor homolog-1 (LRH-1, NR5A2)
DCC3137 Lrh-1 Inhibitor-3 The first small molecule antagonist of LRH-1 activity.
DCC3138 Lsd1 Inhibitor L8 Novel selective and reversible LSD1 inhibitor (IC50 value of 60 nM), exhibiting the antiproliferative activity against HTB5, HTB3, HT1376, and HTB1 cells with IC50 values of 1.87, 0.18, 0.09, and 0.93 μM, respectively
DCC3139 Lsd1-in-c26 Novel selective inhibitor of histone lysine specific demethylase 1 (LSD1/KDM1A), displaying FAD-competitive binding to LSD1, concentration-dependently inducing accumulation of H3K4me1/me2 and H3K9me2, increasing expression levels of epithelial cell marker
DCC3140 Lsf-oa Novel prodrug of Lisofylline, maintaining a steady fasting blood glucose level with a significant increase in insulin level
DCC3141 Lsf-pa Novel prodrug of Lisofylline, maintaining a steady fasting blood glucose level with a significant increase in insulin level
DCC3142 Lsm-4144 First-in-class inhibitor of NF-κB signaling pathway by preventing the maturation of a rate-limiting multiprotein complex necessary for IKK activation
DCC3143 Lsn3160440 Novel positive allosteric modulator (PAM) of the GLP-1R, enhancing insulin secretion in a glucose-, ligand- and GLP-1R-dependent manner

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