DCC3144 |
Lsn3172176 Precursor |
Precursor for 11C-radiolabelling LSN3172176 PET scan |
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DCC3145 |
Lsn335984 Trihydrochloride |
Selective inhibitor of P-glycoproteins (P-gp) |
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DCC3146 |
Lspn451 |
Novel potent xanthine oxidase inhibitor |
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DCC3147 |
Lt-106-175 |
Novel potent inhibitor of FLT3 mutations, also inhibiting CDK2 and CDK6 |
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DCC3148 |
Ethyl-3,4-dephostatin |
Novel inhibitor of the interactions of CFTR-associated ligand (CAL) and PSD-95/Dlg1/ZO-1 (PDZ) domain |
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DCC3149 |
L-threonyl-l-threonine |
Peptide metabolite |
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DCC3150 |
Lturm-36 |
Novel PI 3-kinase delta inhibitor |
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DCC3151 |
Lu Aa27122 |
Brain penetrant high affinity α1A-adrenoceptor ligand |
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DCC3152 |
Lu Aa41063 |
Novel potent and selective hA2A receptor antagonist |
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DCC3153 |
Lu Af58786 |
Novel potent and selective inhibitor of LRRK2, inhibiting LRRK2 WT, the overactive variant G2019S, and the resistant mutant A2016T56 at 12 nM, 19 nM and 93 nM, respectively |
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DCC3154 |
Lu Af58801 |
Novel, potent, selective and brain penetrant positive allosteric modulator of alpha-7 nicotinic acetylcholine receptors |
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DCC3155 |
Lu-001i |
Novel potent and selective LMP2 inhibitor, also inhibiting mouse 20S proteasomes |
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DCC3156 |
Lu-002 |
Novel β2-specific inhibitor, potently targeting both β2c and β2i, displaying moderate trypanocidal activity |
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DCC3157 |
Lu-002c |
Novel potent β2c-specific inhibitor, displaying moderate trypanocidal activity |
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DCC3158 |
Lu-002i |
Novel β2i-specific inhibitor, displaying moderate trypanocidal activity |
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DCC3159 |
Lu-aa47070 |
Potent and selective adenosine A2A receptor antagonist |
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DCC3160 |
Lu-af11205 |
Potent mGlu5 receptor positive allosteric modulator (PAM) |
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DCC3161 |
Luf-5764 |
A1 adenosine receptor antagonist |
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DCC3162 |
Luf-6056 |
Human adenosine A1 receptor antagonist |
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DCC3163 |
Luf-6258 |
Hybrid ortho/allosteric ligand of the adenosine A(1) receptor |
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DCC3164 |
Lugdunin |
Thiazolidine-containing cyclic peptide antibiotic, suppressing growth of species of disease-causing bacteria in that part of the human microbiome |
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DCC3165 |
Luminespib Mesylate |
Novel inhibitor of heat shock protein 90 (Hsp90) |
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DCC3166 |
Luminolate (luminol Sodium Salt) |
Immune modulator with SARS-CoV-2 antiviral activity via a multi-target mechanism including localized, self-limiting reactive oxygen species (ROS) scavenging activities that were demonstrated in a model of lipopolysaccharide (LPS)-induced joint inflammatio |
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DCC3167 |
Lx7101 Hydrochloride |
Novel Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma |
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DCC3168 |
lxrβ-agonist-19 |
Novel selective LXRβ agonist, reducing total brain Aβ |
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DCC3169 |
Lxy6006 |
Novel Manassantin A Derivative, Inhibiting Hypoxia-Inducible Factor 1 and Tumor Growth |
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DCC3170 |
Lxy6090 |
Novel potent HIF-1 inhibitor, also downregulating the protein level of HIF-1alpha, which depended on von Hippel-Lindau for proteasome degradation, showing in vivo anticancer efficacy by decreasing the HIF-1alpha expression in nude mice bearing MX-1 tumor |
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DCC3171 |
Ly2019-005 |
Novel LRRK2 kinase inhibitor against the wild-type and G2019S mutant LRRK2 kinase being 424.40 ± 1.31 nM, 378.80 ± 1.20 nM, respectively |
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DCC3172 |
Ly2019-006 |
Novel LRRK2 kinase inhibitor against the wild-type and G2019S mutant LRRK2 kinase being 1526.00 ± 0.87 nM, 1165.00 ± 1.18 nM, respectively |
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DCC3173 |
Ly2048978 |
Novel, potent, orally-bioavailable kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders |
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