DCC3204 |
M4k2009
Featured
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M4K2209 is a potent, selective BMP type I receptor ALK2 inhibitor with IC50 of 9 nM, >180-fold selective over ALK5 (IC50=2427 nM). |
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DCC3205 |
M4k2127 |
Novel potent and selective ALK2 inhibitor, showing high initial brain uptake, including in the region of interest (pons) |
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DCC3206 |
M4k2163 |
Novel CNS Penetrant ALK2 Inhibitor for the Treatment of Diffuse Intrinsic Pontine Glioma |
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DCC3207 |
M-5mpep |
Partial antagonist of mGlu5 |
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DCC3208 |
M7594_0037 |
Novel Peptide Deformylase (PDF) Inhibitor, having inhibitory activity against HeLa, A549 and MCF-7 |
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DCC3209 |
Mac-0547630 |
Novel potent and selective inhibitor of UppS without off-target effects on membrane potential |
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DCC3210 |
Mac13243 |
Novel inhibitor of the bacterial lipoprotein targeting chaperone, LolA |
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DCC3211 |
Macluraxanthone |
Natural immunomodulator, significantly decreasing TNF-α and IL-10 cytokine production, regulating the NF-κB and MAPK signaling pathways, displaying the strongest antiproliferative effects with IC50 values of 2.84 and 0.95 μM against A431 and HeLa cancer c |
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DCC3212 |
Madtp-372 |
Potent and selective inhibitor of the induction of cytopathic effect by CHIKV and VEEV |
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DCC3213 |
Madurmycin |
Polyether ionophore antibiotic, inhibiting proliferation and induces apoptosis in myoblast cells |
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DCC3214 |
Magl-2102 |
Novel reversible monoacylglycerol lipase (MAGL) inhibitor |
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DCC3215 |
Magnesium L-threonate |
Inhibitor of TNF-α, preventing and restoring memory deficits associated with neuropathic pain |
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DCC3216 |
Magnesium Oxaloacetate |
Inhibitor of the amebicidal activity of activated murine macrophages, helping the parasite to survive within the mouse large intestine and increasing the survival of C. elegans exposed to H2O2 |
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DCC3217 |
Magreth-16a |
Potent CB2 receptor inverse agonist |
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DCC3218 |
Malonganenone A |
Selective modulator of plasmodial Hsp70s with antimalarial activity |
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DCC3219 |
Malp-2
Featured
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Toll-like receptor 2/6 (TLR-2/6) agonist, regulating Lcn2 gene, promoting collateral growth |
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DCC3220 |
Malp-2s |
TLR2/6 agonist, activating the MyD88 pathway, provoking natural killer (NK) cell activation, increasing co-stimulators CD80/86 and CD40 |
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DCC3221 |
Mal-rp |
Novel quantitative chemical probe for live cell labeling and imaging of proteins that are sensitive to redox modifications |
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DCC3222 |
Manassantin A |
Natural anticancer, anti-inflammatory, neuroleptic agent, also having human acyl-CoA:cholesterol acyltransferase (ACAT) inhibitory activities |
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DCC3223 |
Mao-b Inhibitor 58 |
Highly potent, selective, competitive, and reversible inhibitor of monoamine oxidase B (MAO-B). |
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DCC3224 |
Mao-b Inhibitor C3 |
Novel potent and highly selective MAO-B Inhibitor |
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DCC3225 |
Mao-b Inhibitor C5 |
Potent and selective MAO-B inhibitor |
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DCC3226 |
Mao-b Inhibitor Cc1 |
Novel potent selective and competitive inhibitor of MAO-B (IC 50 : 0.69 μM) |
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DCC3227 |
Mao-b Inhibitor Cc2 |
Novel potent and competitive inhibitor of MAO-B (IC 50 : 0.51 μM), also inhibiting BChE (IC 50 : 7.00 μM) |
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DCC3228 |
Mao-b Ligand-1 |
Novel selective MAO-B inhibitor |
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DCC3229 |
Ma-pabc-adc-linker-18 |
Novel stable antibody-drug conjugate (ADC) in mouse serum |
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DCC3230 |
Maprotiline |
Inhibitor of neuronal norepinephrine reuptake, reducing symptoms of anxiety associated with depression. |
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DCC3231 |
Marbotinib |
Novel highly efficient dual type I/II FMS-like tyrosine kinase inhibitor, disrupting the growth of leukemic cells |
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DCC3232 |
Margatoxin |
Inhibitor of voltage-gated K(+) (Kv) channels Kv1.3 and Kv1.5 |
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DCC3233 |
Maritinone |
Novel, active, and less toxic anti-tuberculosis (anti-TB) agent |
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