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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC3204 M4k2009 Featured M4K2209 is a potent, selective BMP type I receptor ALK2 inhibitor with IC50 of 9 nM, >180-fold selective over ALK5 (IC50=2427 nM).
DCC3205 M4k2127 Novel potent and selective ALK2 inhibitor, showing high initial brain uptake, including in the region of interest (pons)
DCC3206 M4k2163 Novel CNS Penetrant ALK2 Inhibitor for the Treatment of Diffuse Intrinsic Pontine Glioma
DCC3207 M-5mpep Partial antagonist of mGlu5
DCC3208 M7594_0037 Novel Peptide Deformylase (PDF) Inhibitor, having inhibitory activity against HeLa, A549 and MCF-7
DCC3209 Mac-0547630 Novel potent and selective inhibitor of UppS without off-target effects on membrane potential
DCC3210 Mac13243 Novel inhibitor of the bacterial lipoprotein targeting chaperone, LolA
DCC3211 Macluraxanthone Natural immunomodulator, significantly decreasing TNF-α and IL-10 cytokine production, regulating the NF-κB and MAPK signaling pathways, displaying the strongest antiproliferative effects with IC50 values of 2.84 and 0.95 μM against A431 and HeLa cancer c
DCC3212 Madtp-372 Potent and selective inhibitor of the induction of cytopathic effect by CHIKV and VEEV
DCC3213 Madurmycin Polyether ionophore antibiotic, inhibiting proliferation and induces apoptosis in myoblast cells
DCC3214 Magl-2102 Novel reversible monoacylglycerol lipase (MAGL) inhibitor
DCC3215 Magnesium L-threonate Inhibitor of TNF-α, preventing and restoring memory deficits associated with neuropathic pain
DCC3216 Magnesium Oxaloacetate Inhibitor of the amebicidal activity of activated murine macrophages, helping the parasite to survive within the mouse large intestine and increasing the survival of C. elegans exposed to H2O2
DCC3217 Magreth-16a Potent CB2 receptor inverse agonist
DCC3218 Malonganenone A Selective modulator of plasmodial Hsp70s with antimalarial activity
DCC3219 Malp-2 Featured Toll-like receptor 2/6 (TLR-2/6) agonist, regulating Lcn2 gene, promoting collateral growth
DCC3220 Malp-2s TLR2/6 agonist, activating the MyD88 pathway, provoking natural killer (NK) cell activation, increasing co-stimulators CD80/86 and CD40
DCC3221 Mal-rp Novel quantitative chemical probe for live cell labeling and imaging of proteins that are sensitive to redox modifications
DCC3222 Manassantin A Natural anticancer, anti-inflammatory, neuroleptic agent, also having human acyl-CoA:cholesterol acyltransferase (ACAT) inhibitory activities
DCC3223 Mao-b Inhibitor 58 Highly potent, selective, competitive, and reversible inhibitor of monoamine oxidase B (MAO-B).
DCC3224 Mao-b Inhibitor C3 Novel potent and highly selective MAO-B Inhibitor
DCC3225 Mao-b Inhibitor C5 Potent and selective MAO-B inhibitor
DCC3226 Mao-b Inhibitor Cc1 Novel potent selective and competitive inhibitor of MAO-B (IC 50 : 0.69 μM)
DCC3227 Mao-b Inhibitor Cc2 Novel potent and competitive inhibitor of MAO-B (IC 50 : 0.51 μM), also inhibiting BChE (IC 50 : 7.00 μM)
DCC3228 Mao-b Ligand-1 Novel selective MAO-B inhibitor
DCC3229 Ma-pabc-adc-linker-18 Novel stable antibody-drug conjugate (ADC) in mouse serum
DCC3230 Maprotiline Inhibitor of neuronal norepinephrine reuptake, reducing symptoms of anxiety associated with depression.
DCC3231 Marbotinib Novel highly efficient dual type I/II FMS-like tyrosine kinase inhibitor, disrupting the growth of leukemic cells
DCC3232 Margatoxin Inhibitor of voltage-gated K(+) (Kv) channels Kv1.3 and Kv1.5
DCC3233 Maritinone Novel, active, and less toxic anti-tuberculosis (anti-TB) agent

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