DCC3234 |
Maropitant Citrate [359875-09-5]
Featured
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Neurokinin receptor antagonist with antiemetic activity |
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DCC3235 |
Massiliamide |
Novel potent tyrosinase inhibitor from the Gram-negative bacterium Massilia albidiflava DSM 17472T |
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DCC3236 |
May1-in-13a |
Novel potent inhibitor of May1 with Ki = 12 ± 1 nM, also inhibiting wild-type HIV-1 protease with Ki = 32 ± 5 pM and three drug resistance-associated mutants with Ki values ranging from 24 to 320 pM |
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DCC3237 |
Maysin |
Natural Anti-inflammation Agent, Attenuating Amyloid Plaques by Inducing Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer's Mouse Model |
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DCC3238 |
Mb-001 |
Novel potent inhibitor of the membrane-bound retinoid isomerase RPE65 |
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DCC3239 |
Mb06322 |
Prodrug of MB05032, acting as potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes |
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DCC3240 |
Mb16695 |
Novel Inhibitor of Mycobacterium tuberculosis α-1,4-Glucan Branching Enzyme (GlgB) |
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DCC3241 |
Mb-211 |
Novel inhibitor of dengue and West Nile virus NS2B-NS3 protease |
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DCC3242 |
Mbls-in-5 |
Novel non-hemolytic and low toxic inhibitor of metallo-β-lactamases (MBLs), restoring the activity of meropenem against Escherichia coli, Citrobacter freundii, Proteus mirabilis and Klebsiella pneumonia, which carried resistance genes of blaNDM-1 |
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DCC3243 |
Mbp-c12 |
Novel detergent, showing enhanced stability to all tested proteins compared to a gold standard detergent (DDM) |
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DCC3244 |
Mbp-c9 |
Novel detergent, showing enhanced stability to all tested proteins compared to a gold standard detergent (DDM) |
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DCC3245 |
Mbri-001 |
Deuterium-substituted anticancer agent, plinabulin, exhibiting better pharmacokinetic characteristics than that of plinabulin |
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DCC3246 |
Mbt-fh Inhibitor-7 |
The first selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase |
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DCC3247 |
Mbx-1066 |
Potent antibacterial agent against a wide range of Gram-positive and Gram-negative bacteria |
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DCC3248 |
Mbx-1162 |
Novel antibacterial agent, remarkably potent against antibiotic-resistant bacterial strains such as MDR A. baumannii , ESBL-producing Klebsiella pneumoniae, VRE, and MRSA |
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DCC3249 |
Mbx-1887 |
Antibacterial agent, with a relatively narrow spectrum against bacteria and a very high CC 50 value |
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DCC3250 |
Mbx2546 |
Novel specific inhibitor of HA-mediated viral entry, inhibiting HPAI H5N1 virus strain A/Hong Kong/H5N1 |
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DCC3251 |
Mc1220 |
Topical nonnucleoside reverse transcriptase inhibitor, partially preventing vaginal RT-SHIV infection of macaques |
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DCC3252 |
Mc-1353 |
Potent and HDAC class I-selective inhibitor |
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DCC3253 |
Mc1420 |
Novel potent acetylcholinesterase (AChE) inhibitor |
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DCC3254 |
Mc-1-f2 |
The first inhibitor of forkhead Box Protein C2 (FOXC2) |
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DCC3255 |
Mc2050 |
Novel selective PARP1 inhibitor, inhibitng apoptosis and blocking poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells |
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DCC3256 |
Mc2392 |
Novel hybrid retinoid-HDAC inhibitor |
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DCC3257 |
Mc-70 Hydrochloride |
Potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively) |
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DCC3258 |
Mca-13 |
Novel neurotropic agent |
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DCC3259 |
Mca-yvadapk(dnp)-oh |
Specific and highly fluorescent substrate for caspase-1, also acting as a substrate for caspase-4 |
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DCC3260 |
Mcc1019 |
Novel selective inhibitor of the Polo-box domain of Polo-like kinase 1 (PLK1) |
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DCC3261 |
Mcc1189 |
First-in-class inhibitor of MFS efflux pump CaMdr1p |
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DCC3262 |
Mcc-134 |
Novel inverse agonist for the pancreatic-type ATP-sensitive K channel as vascular relaxing agent |
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DCC3263 |
MCC950 free acid
Featured
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Potent and selective inhibitor of NLRP3, reducing interleukin-1β (IL-1β) production in vivo and attenuating the severity of experimental autoimmune encephalomyelitis (EAE) |
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