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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC3264 Mc-doxhzn Albumin-binding prodrug of Doxorubicin
DCC3265 Mcg315 Novel potent F508del-CFTR corrector, modulating poly-ADP ribose polymerase 3 and poly-ADP ribose polymerase 16 activities
DCC3266 Mci-225 Selective NA reuptake inhibitor with 5-HT3 receptor antagonism
DCC3267 Mcl0527-3 Novel inhibitor of p53-MDM2 interaction
DCC3268 Mcl-1 Degrader C3 Novel potent and selective degrader of Mcl-1
DCC3269 Mcl-1 Inhibitor-11 Novel reversible covalent inhibitor for Mcl-1 with improved water solubility than Mcl-1 Inhibitor-5
DCC3270 Mcl-1 Inhibitor-39 Novel selective Mcl-1 inhibitor
DCC3271 Mcl-1 Inhibitor-5 The first reversible covalent inhibitor for Mcl-1, a protein-protein interaction (PPI) target
DCC3272 Mcl1-in-1 Novel potent and selective inhibitor of the apoptosis regulating proteins Mcl-1
DCC3273 Mcmmad Featured Novel mc (maleimidocaproyl) linker plus MMAD (Monomethylauristatin D) to be used for prepare antibodies conjugates via cysteine-capped mechanism
DCC3274 Mct4-in-18n Novel highly selective inhibitor of monocarboxylate transporter 4 (MCT4/SLC16A3), resulting in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells
DCC3275 Mcule-5948770040 Novel SARS-CoV-2 Main Protease (Mpro) inhibitor, binding to Subsites S1 and S2 (Kd=1.3 µM)
DCC3276 Md-222 First-in-class highly potent PROTAC degrader of MDM2
DCC3277 Md-39-am Diuretic agent, impling an increase in the Na+ excretion and showing antihypertensive effect
DCC3278 Mdc-1112 Novel valproic acid (VPA) derivative, as a potent STAT3 inhibitor
DCC3279 Mdcccl1636 Novel partial PPARgamma ligand, displaying partial agonist activity in biochemical and cell-based transactivation assays, and reversed insulin resistance
DCC3280 Mdctmp Novel proteolysis-resistant self-localizing ligand (SL), sustaining PM localization of eDHFR-fusion proteins (over several hours to a day), inducing prolonged signal activation and cell differentiation
DCC3281 Mde 6-82-1c Novel MC5R antagonist
DCC3282 Mde10-136rs Novel potent and highly selective melanocortin-3 receptor (MC3R) agonist, showing greater than 140-fold selective for the mMC3R over the mMC4R, possessed 70 nM potency at the mMC3R, and partially stimulated the mMC4R at 100 μM concentrations without antag
DCC3283 Mde6-5-2c Novel potent and nonselective MC3R and MC4R macrocyclic agonist. decreased food intake and respiratory exchange ratio (RER)
DCC3284 Mdg486 Novel Inhibitor of BAF, activating latent HIV-1
DCC3285 mdg559 Novel peroxisome proliferator activated receptor
DCC3286 mdg582 Novel peroxisome proliferator activated receptor γ (PPARγ) ligand
DCC3287 Mdl100240 Dual inhibitor of angiotensin-converting enzyme and neutral endopeptidase
DCC3288 Mdm2/x Pdi Potent Peptide dual inhibitor of MDM2/X, inhibiting p53 interactions with MDM2 (IC50 = 10 nmol/L) and MDMX (IC50 = 100 nmol/L), inducing apoptosis and cell cycle arrest of cell lines with overexpressed MDM2/X
DCC3289 Mdm2/xiap-in-14 Novel potent dual MDM2/XIAP inhibitor
DCC3290 Mdm2-p53-in-1b Novel inhibitor of the MDM2-p53 interaction
DCC3291 Mdmb-chminaca Potent ligand of the central CB1 receptor
DCC3292 Me1111 Novel selective inhibitor of succinate dehydrogenase (complex II) of dermatophyte species
DCC3293 me6tren Tetrahydrochloride Potent and efficacious mobilizing agent of hematopoietic stem and progenitor cells (HSPCs), activating MMP-9 expression and disrupting the SDF-1α/CXCR4 axis, exhibiting more significant mobilizing effects than G-CSF or AMD3100

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