DCC4045 |
Pd-160725 Isethionate |
AMPA receptor antagonist |
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DCC4046 |
Pd-161989 Isethionate |
AMPA receptor antagonist |
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DCC4047 |
Pd-174494 |
Novel, potent, and selective NR1/2B NMDA receptor antagonist |
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DCC4048 |
P-d1ago |
Novel cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors |
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DCC4049 |
Pd26-tl07 |
Novel selective inhibitor of STAT3 phosphorylation, binding to the SH2 domain of STAT3, exhibiting remarkable antiproliferative activity against three cancer cell lines (HCT-116, SW480 and MDA-MB-231) |
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DCC4050 |
pda-66 |
Novel inducer of mitotic arrest and apoptosis in human progenitor and cancer cells |
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DCC4051 |
Pdd4091 |
Novel G6PD inhibitor |
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DCC4052 |
Pde5-in-42 |
Potent and selective second-generation phosphodiesterase type 5 (PDE5) inhibitor |
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DCC4053 |
Pde7 Inhibitor S14 |
Novel cell-permeable PDE7 inhibitor, targeting the cyclic adenosine monophosphate (cAMP)/cAMP-response element binding protein (CREB) pathway, exerting neuroprotection in an Alzheimer's disease (AD) model |
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DCC4054 |
Pde9-in-16 |
Novel selective PDE9 inhibitor with strong antioxidant activity, inhibiting Aβ aggregation as potential candidates for the treatment of Alzheimer’s disease |
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DCC4055 |
Pde9-in-2 |
Novel Potent, Selective, and Orally Bioavailable Inhibitor against Phosphodiesterase-9 (PDE9) |
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DCC4056 |
P-decylaminophenol |
Novel inhibitor of melanogenesis |
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DCC4057 |
Pdf Inhibitor M-2 |
Novel Peptide Deformylase (PDF) Inhibitor |
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DCC4058 |
Pdi-in-p1 |
Protein disulfide isomerase (PDI) inhibitor |
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DCC4059 |
Pd-l1 Degrader F4 |
Novel PD-L1 degrader, showing 66.99% degradation activity at 20 μM with no calcium blocking effect, strengthening the T cell-mediated killing of tumor cells |
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DCC4060 |
Pd-l1 Degrader P22 |
Novel PROTAC dual inhibitor and degrader of PD-L1, inhibiting PD-1/PD-L1 interaction with IC50 of 39.2 nM in an HTRF binding assay |
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DCC4061 |
Pd-l1 Inhibitor L7 |
Novel Potent PD-L1 Inhibitor (IC50 1.8 nM), binding to human PD-L1 (hPD-L1) with a KD value of 3.34 nM, without showing any binding to hPD-1, blocking PD-1/PD-L1 interaction with an EC50 value of 375 nM |
|
DCC4062 |
Pdsinh-c01 |
Novel pendrin inhibitor, inhibiting Cl-/anion exchange mediated by mouse pendrin without affecting other major kidney tubule transporters |
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DCC4063 |
Peg-vtx |
Novel polyethylene glycol (PEG)-drug conjugate of Venetoclax, a Bcl-2 inhibitor, for treatment of acute myeloid leukemia (AML) |
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DCC4064 |
Pelorol |
Activator of SHIP-1 |
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DCC4065 |
pemedolac |
Cyclooxygenase Inhibitor and Prostagladin Synthase Inhibitor |
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DCC4066 |
Penb-l-glutamate |
Novel caged glutamate |
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DCC4067 |
Penclomedine |
Antineoplastic agent, alkylating and crosslinking DNA, resulting in DNA strand breaks and inhibition of DNA and RNA synthesis |
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DCC4068 |
Penicillic Acid |
Mycotoxin with antibiotic and carcinogenic activity |
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DCC4069 |
penicillin K |
Antibiotic, a natural penicillin, synthesized in vitro by incubating (S-octanoyl)glutathione, 6-APA and AT |
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DCC4070 |
Penindolone |
Novel potent and broad-spectrum anti-influenza A virus (anti-IAV) activities with low risk of inducing drug resistance |
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DCC4071 |
Pentamidine Dimesylate |
Inhibitor of calcium-dependent complex formation with p53 [(Ca)S100B-p53] in malignant melanoma (MM), restoring p53 tumor suppressor activity in vivo |
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DCC4072 |
Peptide 1018 |
Innate defense regulator, target stringent response-controlled virulence in a Pseudomonas aeruginosa murine cutaneous infection model |
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DCC4073 |
Peptide 4f |
ApoA-I/HDL mimetic peptide, efficiently crossing the blood-brain barrier and modulating amyloid beta distribution between brain and plasma |
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DCC4074 |
Peptide P9r |
Broad-spectrum virus- and host-targeting peptide, inhibiting coronaviruses and other respiratory viruses |
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